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centrosome duplication

Known as: centrosome replication 
The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle… 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

centriole replication

Broader (1)

centrosome cycle
regulation of centrosome duplication

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
RhoD participates in the regulation of cell-cycle progression and centrosome duplication
We have previously identified a Rho protein, RhoD, which localizes to the plasma membrane and the early endocytic compartment… 
Highly Cited
2010
Highly Cited
2010
A Centrosome-autonomous Signal That Involves Centriole Disengagement Permits Centrosome Duplication in G2 Phase after DNA Damage
How centrosomes amplify after DNA damage is unclear. Cell fusions demonstrated that only irradiated centrosomes duplicate when… 
2010
2010
Antizyme Restrains Centrosome Amplification by Regulating the Accumulation of Mps1 at Centrosomes
The failure to degrade Mps1 at centrosomes causes centrosome overproduction, but the factors that target Mps1 for degradation are… 
2010
2010
3-Methyladenine blocks Toxoplasma gondii division prior to centrosome replication.
2009
2009
Budding Yeast Centrosome Duplication Requires Stabilization of Spc29 via Mps1-mediated Phosphorylation*
Protein phosphorylation plays an important role in the regulation of centrosome duplication. In budding yeast, numerous lines of… 
Highly Cited
2008
Highly Cited
2008
Differential regulation of centrosome integrity by DNA damage response proteins
MDC1 and BRIT1 have been shown to function as key regulators in response to DNA damage. However, their roles in centrosomal… 
Highly Cited
2006
Highly Cited
2006
Inhibition of BRCA1 in breast cell lines causes the centrosome duplication cycle to be disconnected from the cell cycle
BRCA1-dependent ubiquitination activity regulates centrosome number in several tissue culture cell lines derived from breast… 
2004
2004
Centrosome‐targeting region of CG‐NAP causes centrosome amplification by recruiting cyclin E‐cdk2 complex
Centrosome duplication occurs once per cell cycle and is thought to be triggered by cyclin E‐cdk2. However, it is largely unknown… 
2000
2000
A subset of centrosomal proteins are arranged in a tubular conformation that is reproduced during centrosome duplication.
The centrosome plays a fundamental role in organizing the interphase cytoskeleton and the mitotic spindle, and its protein… 
Highly Cited
1999
Highly Cited
1999
Stress fibres take shape
The GTPase Rho is well known for its ability to induce the assembly of stress fibres. Two interacting targets of Rho, ROCK and… 
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