centrosome duplication

Known as: centrosome replication 
The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle… (More)
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
The centrosome organizes the microtubule cytoskeleton and consists of a pair of centrioles surrounded by pericentriolar material… (More)
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Highly Cited
2002
Highly Cited
2002
Centrosome duplication and separation are linked inextricably to certain cell cycle events, in particular activation of cyclin… (More)
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Highly Cited
2002
Highly Cited
2002
Aberrations in centrosome numbers have long been implicated in aneuploidy and tumorigenesis, but their origins are unknown. Here… (More)
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Highly Cited
2002
Highly Cited
2002
Budding yeast Mps1p kinase has been implicated in both the duplication of microtubule-organizing centers and the spindle assembly… (More)
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Highly Cited
2001
Highly Cited
2001
The yeast Mps1p protein kinase acts in centrosome duplication and the spindle assembly checkpoint. We demonstrate here that a… (More)
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Highly Cited
2000
Highly Cited
2000
In animal cells, duplication of centrosomes and DNA is coordinated. Since CDK2/cyclin E triggers initiation of both events… (More)
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Review
2000
Review
2000
The yeast spindle pole body (SPB) is the functional equivalent of the centrosome and forms the two poles of the mitotic spindle… (More)
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Highly Cited
1999
Highly Cited
1999
Centrosomes nucleate microtubules and duplicate once per cell cycle. This duplication and subsequent segregation in mitosis… (More)
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Highly Cited
1999
Highly Cited
1999
Centrosome duplication is a key requirement for bipolar spindle formation and correct segregation of chromosomes during cell… (More)
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Highly Cited
1999
Highly Cited
1999
Centrosome duplication is indispensable for the formation of the bipolar mitotic spindle. Surprisingly, even if DNA replication… (More)
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