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centhaquine

Known as: 1-(bis(2-quinolyl)ethyl)-4-m-tolylpiperazine, Quinoline, 2-(2-(4-(3-methylphenyl)-1-piperazinyl)ethyl)-, centhaquin 
National Institutes of Health

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Piperazines

Papers overview

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2016
2016
Pharmacokinetics of centhaquin citrate in a rat model
Centhaquin citrate is a novel agent being developed for use in the treatment of haemorrhagic shock. It has decreased mortality in… 
2016
2016
Centhaquin attenuates hyperalgesia and non-evoked guarding in a rat model of postoperative pain primarily through α2B-adrenoceptors.
2016
2016
Pharmacokinetics of centhaquin citrate in a dog model
Centhaquin citrate is a novel agent that is being developed for use in the resuscitation of patients with haemorrhagic shock… 
2014
2014
Synthesis and Characterization of Centhaquin and its Citrate Salt and a Comparative Evaluation of their Cardiovascular Actions
Abstract Centhaquin is a compound that produces hypotension and bradycardia in higher doses and resuscitation in lower doses. It… 
2013
2013
Efficacy of centhaquin as a small volume resuscitative agent in severely hemorrhaged rats.
2013
2013
534: Resuscitative efficacy of centhaquin in a rabbit model of uncontrolled hemorrhagic shock
2012
2012
Repeated Administration of Centhaquin to Pregnant Rats did not Affect Postnatal Development and Expression of Endothelin Receptors in the Brain, Heart or Kidney of Pups
Abstract The effect of repeated administration of centhaquin to pregnant rats on postnatal development, and expression of ETA and… 
2012
2012
587: ALPHA ADRENERGIC RECEPTORS MEDIATE RESUSCITATIVE EFFECT OF CENTHAQUIN IN HEMORRHAGED RATS
1997
1997
Attenuation in rat brain nitric oxide synthase activity in the coarctation model of hypertension.
The correlation of brain nitric oxide synthase (NOS) activity with renal hypertension has been investigated in rats. NOS activity… 
1990
1990
Pharmacological studies on 2-(2-(4-(3-methylphenyl)-1-piperazinyl)ethyl) quinoline (centhaquin). I. Hypotensive activity.
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