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cefclidin
Known as:
(+)-1-(((6R,7R)-7-(2-(5-Amino-1,2,4-thiadiazol-3-yl)glyoxylamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-4-carbamoylquinuclidinium Hydroxide, Inner Salt, 7(sup 2)-(Z)-(O-methyloxime)
, 3-((4-carbamoyl-1-quinuclidinio)methyl)-7-(2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetamido)-8-oxo-5-thia-1-azabicyclo(4,2,0)oct-2-ene-2-carboxylate
, Cefaclidine
A fourth-generation, parenteral cephalosporin with strong activity against glucose non-fermentative bacillus bacteria, but is ineffective against…
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National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Cephalosporins
Narrower (1)
E 1040
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Oxacillinase-Mediated Resistance to Cefepime and Susceptibility to Ceftazidime in Pseudomonas aeruginosa
D. Aubert
,
L. Poirel
,
J. Chevalier
,
S. Léotard
,
J. Pagés
,
P. Nordmann
Antimicrobial Agents and Chemotherapy
2001
Corpus ID: 6487256
ABSTRACT Pseudomonas aeruginosa clinical isolate SOF-1 was resistant to cefepime and susceptible to ceftazidime. This resistance…
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Highly Cited
1999
Highly Cited
1999
Detection of OXA-4 beta-lactamase in Pseudomonas aeruginosa isolates by genetic methods.
K. Marumo
,
A. Takeda
,
Y. Nakamura
,
K. Nakaya
The Journal of antimicrobial chemotherapy
1999
Corpus ID: 17657631
In Pseudomonas aeruginosa, resistance to cefclidin is usually associated with resistance to another third-generation…
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1996
1996
Antibacterial in vitro activity of fourth generation cephalosporins.
R. Hancock
,
F. Bellido
Journal of chemotherapy
1996
Corpus ID: 24475700
Cefpirome, cefepime and cefaclidine are distinguished by having a positively charged quaternary ammonium at carbon 3 of the…
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Highly Cited
1996
Highly Cited
1996
Quantitative correlation between susceptibility and OprJ production in NfxB mutants of Pseudomonas aeruginosa
N. Masuda
,
N. Gotoh
,
S. Ohya
,
T. Nishino
Antimicrobial agents and chemotherapy
1996
Corpus ID: 22808031
Various Pseudomonas aeruginosa PAO1 NfxB mutants were isolated on agar plates containing cefpirome and ofloxacin. They were…
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1995
1995
Epidemiology of Prostate Disease
M. Garraway
Springer Berlin Heidelberg
1995
Corpus ID: 34085937
This reference book helps to identify the role of medical and surgical therapies in the treatment of benign prostate hyperplasia…
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1995
1995
Purification and Characterization of Metallo‐β‐Lactamase from Serratia marcescens
K. Marumo
,
A. Takeda
,
Y. Nakamura
,
K. Nakaya
Microbiology and immunology
1995
Corpus ID: 23768809
Carbapenem‐hydrolyzing β‐lactamase from Serratia marcescens FHSM4055 was purified 926‐fold by means of carboxylmethyl Sephadex C…
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Review
1995
Review
1995
Laboratory assessment of antibacterial activity of zwitterionic 7-methoxyimino cephalosporins.
J. Pechère
,
W. Wilson
,
H. Neu
The Journal of antimicrobial chemotherapy
1995
Corpus ID: 1072844
Zwitterionic 7-methoxyimino cephalosporins (cefpirome, cefepime, cefclidin, DQ2556, FK037 and SCE2787) possess a variable…
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Highly Cited
1993
Highly Cited
1993
Therapeutic effect of cefozopran (SCE-2787), a new parenteral cephalosporin, against experimental infections in mice
Y. Iizawa
,
K. Okonogi
,
R. Hayashi
,
T. Iwahi
,
T. Yamazaki
,
A. Imada
Antimicrobial Agents and Chemotherapy
1993
Corpus ID: 36612328
The therapeutic effect of cefozopran (SCE-2787), a new semisynthetic parenteral cephalosporin, against experimental infections in…
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1992
1992
Role of the aminothiadiazolyl group in the antipseudomonal activity of cefclidin.
N. Watanabe
,
I. Sugiyama
The Journal of antibiotics
1992
Corpus ID: 21407734
Cefclidin (E1040), which has an aminothiadiazolyl group in the 7 beta-side chain, showed about four-fold higher activity against…
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Highly Cited
1991
Highly Cited
1991
Comparison of cefepime, cefpirome, and cefaclidine binding affinities for penicillin-binding proteins in Escherichia coli K-12 and Pseudomonas aeruginosa SC8329
M. Pucci
,
J. Boice-Sowek
,
R. Kessler
,
T. Dougherty
Antimicrobial Agents and Chemotherapy
1991
Corpus ID: 13215455
The relative binding affinities of the extended-spectrum cephalosporins cefepime, cefpirome, and cefaclidine for the penicillin…
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