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cefclidin

Known as: (+)-1-(((6R,7R)-7-(2-(5-Amino-1,2,4-thiadiazol-3-yl)glyoxylamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-4-carbamoylquinuclidinium Hydroxide, Inner Salt, 7(sup 2)-(Z)-(O-methyloxime), 3-((4-carbamoyl-1-quinuclidinio)methyl)-7-(2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetamido)-8-oxo-5-thia-1-azabicyclo(4,2,0)oct-2-ene-2-carboxylate, Cefaclidine 
A fourth-generation, parenteral cephalosporin with strong activity against glucose non-fermentative bacillus bacteria, but is ineffective against… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Cephalosporins

Narrower (1)

E 1040

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Oxacillinase-Mediated Resistance to Cefepime and Susceptibility to Ceftazidime in Pseudomonas aeruginosa
ABSTRACT Pseudomonas aeruginosa clinical isolate SOF-1 was resistant to cefepime and susceptible to ceftazidime. This resistance… 
Highly Cited
1999
Highly Cited
1999
Detection of OXA-4 beta-lactamase in Pseudomonas aeruginosa isolates by genetic methods.
In Pseudomonas aeruginosa, resistance to cefclidin is usually associated with resistance to another third-generation… 
1996
1996
Antibacterial in vitro activity of fourth generation cephalosporins.
Cefpirome, cefepime and cefaclidine are distinguished by having a positively charged quaternary ammonium at carbon 3 of the… 
Highly Cited
1996
Highly Cited
1996
Quantitative correlation between susceptibility and OprJ production in NfxB mutants of Pseudomonas aeruginosa
Various Pseudomonas aeruginosa PAO1 NfxB mutants were isolated on agar plates containing cefpirome and ofloxacin. They were… 
1995
1995
Epidemiology of Prostate Disease
  • M. Garraway
  • Springer Berlin Heidelberg
  • 1995
  • Corpus ID: 34085937
This reference book helps to identify the role of medical and surgical therapies in the treatment of benign prostate hyperplasia… 
1995
1995
Purification and Characterization of Metallo‐β‐Lactamase from Serratia marcescens
Carbapenem‐hydrolyzing β‐lactamase from Serratia marcescens FHSM4055 was purified 926‐fold by means of carboxylmethyl Sephadex C… 
Review
1995
Review
1995
Laboratory assessment of antibacterial activity of zwitterionic 7-methoxyimino cephalosporins.
Zwitterionic 7-methoxyimino cephalosporins (cefpirome, cefepime, cefclidin, DQ2556, FK037 and SCE2787) possess a variable… 
Highly Cited
1993
Highly Cited
1993
Therapeutic effect of cefozopran (SCE-2787), a new parenteral cephalosporin, against experimental infections in mice
The therapeutic effect of cefozopran (SCE-2787), a new semisynthetic parenteral cephalosporin, against experimental infections in… 
1992
1992
Role of the aminothiadiazolyl group in the antipseudomonal activity of cefclidin.
Cefclidin (E1040), which has an aminothiadiazolyl group in the 7 beta-side chain, showed about four-fold higher activity against… 
Highly Cited
1991
Highly Cited
1991
Comparison of cefepime, cefpirome, and cefaclidine binding affinities for penicillin-binding proteins in Escherichia coli K-12 and Pseudomonas aeruginosa SC8329
The relative binding affinities of the extended-spectrum cephalosporins cefepime, cefpirome, and cefaclidine for the penicillin… 
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