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cefclidin

Known as: (+)-1-(((6R,7R)-7-(2-(5-Amino-1,2,4-thiadiazol-3-yl)glyoxylamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-4-carbamoylquinuclidinium Hydroxide, Inner Salt, 7(sup 2)-(Z)-(O-methyloxime), 3-((4-carbamoyl-1-quinuclidinio)methyl)-7-(2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetamido)-8-oxo-5-thia-1-azabicyclo(4,2,0)oct-2-ene-2-carboxylate, Cefaclidine 
A fourth-generation, parenteral cephalosporin with strong activity against glucose non-fermentative bacillus bacteria, but is ineffective against… Expand
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Cephalosporins

Narrower (1)

E 1040

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Oxacillinase-Mediated Resistance to Cefepime and Susceptibility to Ceftazidime in Pseudomonas aeruginosa
ABSTRACT Pseudomonas aeruginosa clinical isolate SOF-1 was resistant to cefepime and susceptible to ceftazidime. This resistance… Expand
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Highly Cited
1999
Highly Cited
1999
Detection of OXA-4 beta-lactamase in Pseudomonas aeruginosa isolates by genetic methods.
In Pseudomonas aeruginosa, resistance to cefclidin is usually associated with resistance to another third-generation… Expand
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1996
1996
Antibacterial in vitro activity of fourth generation cephalosporins.
Cefpirome, cefepime and cefaclidine are distinguished by having a positively charged quaternary ammonium at carbon 3 of the… Expand
Highly Cited
1996
Highly Cited
1996
Quantitative correlation between susceptibility and OprJ production in NfxB mutants of Pseudomonas aeruginosa.
Various Pseudomonas aeruginosa PAO1 NfxB mutants were isolated on agar plates containing cefpirome and ofloxacin. They were… Expand
1995
1995
Epidemiology of Prostate Disease
  • M. Garraway
  • Springer Berlin Heidelberg
  • 1995
    • Corpus ID: 34085937
This reference book helps to identify the role of medical and surgical therapies in the treatment of benign prostate hyperplasia… Expand
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Review
1995
Review
1995
Laboratory assessment of antibacterial activity of zwitterionic 7-methoxyimino cephalosporins.
Zwitterionic 7-methoxyimino cephalosporins (cefpirome, cefepime, cefclidin, DQ2556, FK037 and SCE2787) possess a variable… Expand
1994
1994
Bacterial biofilm in chronic airway infection.
  • N. Ohgaki
  • Kansenshogaku zasshi. The Journal of the Japanese…
  • 1994
    • Corpus ID: 1985347
We hypothesized that bacterial biofilm formation could be an important factor that makes some infections intractable, and… Expand
Highly Cited
1993
Highly Cited
1993
Therapeutic effect of cefozopran (SCE-2787), a new parenteral cephalosporin, against experimental infections in mice.
The therapeutic effect of cefozopran (SCE-2787), a new semisynthetic parenteral cephalosporin, against experimental infections in… Expand
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1992
1992
Bactericidal activity of cefclidin (E1040) against Pseudomonas aeruginosa under conditions simulating plasma pharmacokinetics: lack of development of chromosomally-mediated resistance to beta-lactams…
The bactericidal activity of cefclidin (E1040), a new cephalosporin, against Pseudomonas aeruginosa was compared with that of… Expand
Highly Cited
1991
Highly Cited
1991
Comparison of cefepime, cefpirome, and cefaclidine binding affinities for penicillin-binding proteins in Escherichia coli K-12 and Pseudomonas aeruginosa SC8329.
The relative binding affinities of the extended-spectrum cephalosporins cefepime, cefpirome, and cefaclidine for the penicillin… Expand
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