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cefcanel

Known as: (6R-(6 alpha,7 beta(R*)))-7-((hydroxyphenylacetyl)amino)-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene- 2-carboxylic acid, 3-(2-(5-methyl-1,3,4-thiadiazyl)mercaptomethyl)-7-(D-(-)-mandelamido)-3-cephem-4-carboxylic acid 
A semisynthetic third-generation cephalosporin with antibacterial activity. Cefcanel binds to and inactivates penicillin-binding proteins (PBPs… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Cefazolin

Narrower (1)

KY 087
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Discovery of DEBIC to correlate P-selectin inhibition and DNA intercalation in cancer therapy and complicated thrombosis
Arterial thrombosis is one of the major complications of cancer and can seriously worsen the prognosis of the patients. These… 
Review
2000
Review
2000
Novel oral cephalosporins
The therapeutic use of oral cephalosporins to treat infectious diseases continues to challenge clinicians; many attempts have… 
1994
1994
Pharmacokinetics of oral cefcanel daloxate hydrochloride in healthy volunteers and patients with various degrees of impaired renal function.
Cefcanel daloxate hydrochloride is a new oral cephalosporin prodrug. It is a double cephem ester of cefcanel, which is the active… 
1993
1993
Antibacterial activity of cefcanel.
The minimum inhibitory concentration of cefcanel, a new oral cephalosporin, has been determined for 182 clinical isolates, of… 
Highly Cited
1991
Highly Cited
1991
Pharmacodynamic effects of subinhibitory concentrations of beta-lactam antibiotics in vitro
The pharmacodynamic effects of subinhibitory concentrations of different beta-lactam antibiotics were investigated. A… 
1991
1991
In vitro activity of cefcanel versus other oral cephalosporins
Cefcanel is a new orally absorbed cephalosporin. Its activity was compared with that of cefuroxime, cefaclor, cephalexin, and… 
1991
1991
Efficacy of cefcanel on staphylocci.
The minimum inhibitory concentration (MIC) of cefcanel, a new oral cephalosporin, has been tested against 153 staphylococci… 
1990
1990
The postantibiotic effect of cefcanel on beta-hemolytic streptococci group A in vitro and in vivo.
The postantibiotic effect (PAE) of cefcanel, a new oral cephalosporin with high in vitro activity against Gram-positive bacteria… 
1989
1989
In vitro activities of cefcanel and some other cephalosporins against Pasteurella multocida
Thirty-five strains of Pasteurella multocida from humans and animals were tested for susceptibility to five cephalosporins by a… 
1989
1989
Comparative antibacterial activity of the new cephalosporin cefcanel against anaerobic bacteria
The activity of cefcanel against anaerobic cocci,Clostridium perfringens, Bacteroides fragilis, Bacteroides spp. and fusobacteria… 
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