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carbobenzoxy-leucyl-leucyl-norvalinal

Known as: Cbz-Leu-Leu-norvalinal, carbobenzoxyl-leucinyl-leucinyl-norvalinal-H, N-carbobenzoxyl-L-leucinyl-L-leucinyl-L-norvalinal 
 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

LeupeptinsProtease Inhibitors

Narrower (2)

MG 115carbobenzyloxy-leucyl-leucyl-norvalinal

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
z-Leucinyl-Leucinyl-Norleucinal Induces Apoptosis of Human Glioblastoma Tumor–Initiating Cells by Proteasome Inhibition and Mitotic Arrest Response
γ-secretase inhibitors have been proposed as drugs able to kill cancer cells by targeting the NOTCH pathway. Here, we… Expand
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Highly Cited
2004
Highly Cited
2004
Porphyromonas gingivalis Induces Receptor Activator of NF-κB Ligand Expression in Osteoblasts through the Activator Protein 1 Pathway
ABSTRACT Porphyromonas gingivalis, an important periodontal pathogen, is closely associated with inflammatory alveolar bone… Expand
2003
2003
IκB overexpression in cardiomyocytes prevents NF-κB translocation and provides cardioprotection in trauma
This study examined the effects of either IκBα overexpression (transgenic mice) orN-acetyl-leucinyl-leucinyl-norleucinal (ALLN… Expand
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Highly Cited
2002
Highly Cited
2002
A proteasome inhibitor confers cardioprotection.
OBJECTIVE In several cell types, proteasome inhibitors like carbobenzoxyl-leucinyl-leucinyl-leucinal (MG132) induce the 72 kDa… Expand
2002
2002
Intracellular mechanisms mediating the inhibition of apoB-containing lipoprotein synthesis and secretion in HepG2 cells by avasimibe (CI-1011), a novel acyl-coenzyme A: cholesterol acyltransferase…
We have studied the cellular and molecular mechanisms involved in the suppression of apoB secretion from HepG2 cells following… Expand
2001
2001
Proteasomal activation mediates down-regulation of inositol 1,4,5-trisphosphate receptor and calcium mobilization in rat pancreatic islets.
Inositol 1,4,5-trisphosphate receptor (IP3R) protein levels in isolated rat pancreatic islets were investigated in response to… Expand
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2001
2001
Differentiation‐dependent sensitivity to cell death induced in the developing retina by inhibitors of the ubiquitin‐proteasome proteolytic pathway
The effects of inhibitors of proteasome function were studied in the retina of developing rats. Explants from the retina of… Expand
2001
2001
Reversal of physiological stress-induced resistance to topoisomerase II inhibitors using an inducible phosphorylation site-deficient mutant of I kappa B alpha.
Physiological stress conditions associated with the tumor microenvironment play a role in resistance to anticancer therapy. In… Expand
Highly Cited
1999
Highly Cited
1999
Depolarization regulates cyclin D1 degradation and neuronal apoptosis: a hypothesis about the role of the ubiquitin/proteasome signalling pathway
Depolarization and subsequent calcium entry exert essential neuroprotective effects but the ultimate effector by which calcium… Expand
1998
1998
Enhanced in vitro cytotoxicity and cytostasis of the combination of onconase with a proteasome inhibitor.
In proliferating cells the turnover rate of proteins responsible for regulation of the cell cycle progression, namely cyclins and… Expand
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