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carbobenzoxy-leucyl-leucyl-norvalinal

Known as: Cbz-Leu-Leu-norvalinal, carbobenzoxyl-leucinyl-leucinyl-norvalinal-H, N-carbobenzoxyl-L-leucinyl-L-leucinyl-L-norvalinal 
 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

LeupeptinsProtease Inhibitors

Narrower (2)

MG 115carbobenzyloxy-leucyl-leucyl-norvalinal

Papers overview

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2009
2009
z-Leucinyl-Leucinyl-Norleucinal Induces Apoptosis of Human Glioblastoma Tumor–Initiating Cells by Proteasome Inhibition and Mitotic Arrest Response
γ-secretase inhibitors have been proposed as drugs able to kill cancer cells by targeting the NOTCH pathway. Here, we… Expand
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2004
2004
Porphyromonas gingivalis induces receptor activator of NF-kappaB ligand expression in osteoblasts through the activator protein 1 pathway.
Porphyromonas gingivalis, an important periodontal pathogen, is closely associated with inflammatory alveolar bone resorption… Expand
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2003
2003
IκB overexpression in cardiomyocytes prevents NF-κB translocation and provides cardioprotection in trauma
This study examined the effects of either IκBα overexpression (transgenic mice) or N -acetyl-leucinyl-leucinyl-norleucinal (ALLN… Expand
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2002
2002
A proteasome inhibitor confers cardioprotection.
OBJECTIVE In several cell types, proteasome inhibitors like carbobenzoxyl-leucinyl-leucinyl-leucinal (MG132) induce the 72 kDa… Expand
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2002
2002
Intracellular mechanisms mediating the inhibition of apoB-containing lipoprotein synthesis and secretion in HepG2 cells by avasimibe (CI-1011), a novel acyl-coenzyme A: cholesterol acyltransferase…
We have studied the cellular and molecular mechanisms involved in the suppression of apoB secretion from HepG2 cells following… Expand
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2001
2001
Proteasomal activation mediates down-regulation of inositol 1,4,5-trisphosphate receptor and calcium mobilization in rat pancreatic islets.
Inositol 1,4,5-trisphosphate receptor (IP3R) protein levels in isolated rat pancreatic islets were investigated in response to… Expand
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2001
2001
Differentiation-dependent sensitivity to cell death induced in the developing retina by inhibitors of the ubiquitin-proteasome proteolytic pathway.
The effects of inhibitors of proteasome function were studied in the retina of developing rats. Explants from the retina of… Expand
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2001
2001
Reversal of physiological stress-induced resistance to topoisomerase II inhibitors using an inducible phosphorylation site-deficient mutant of I kappa B alpha.
Physiological stress conditions associated with the tumor microenvironment play a role in resistance to anticancer therapy. In… Expand
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1999
1999
Depolarization regulates cyclin D1 degradation and neuronal apoptosis: a hypothesis about the role of the ubiquitin/proteasome signalling pathway.
Depolarization and subsequent calcium entry exert essential neuroprotective effects but the ultimate effector by which calcium… Expand
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1998
1998
Enhanced in vitro cytotoxicity and cytostasis of the combination of onconase with a proteasome inhibitor.
In proliferating cells the turnover rate of proteins responsible for regulation of the cell cycle progression, namely cyclins and… Expand
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