FAQ

carbobenzoxy-leucyl-leucyl-norvalinal

Known as: Cbz-Leu-Leu-norvalinal, carbobenzoxyl-leucinyl-leucinyl-norvalinal-H, N-carbobenzoxyl-L-leucinyl-L-leucinyl-L-norvalinal 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2014
02419972014

Related topics

Related topics

4 relations

Broader (2)

LeupeptinsProtease Inhibitors

Narrower (2)

MG 115carbobenzyloxy-leucyl-leucyl-norvalinal

Related mentions per year

Related mentions per year

1944-2018
19401960198020002020
carbobenzoxy-leucyl-leucyl-norvalinal
Protease Inhibitors
MG 115
Leupeptins
carbobenzyloxy-leucyl-leucyl-norvalinal

Papers overview

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2015
2015
MG132 enhances the radiosensitivity of lung cancer cells in vitro and in vivo.
Radiotherapy is a common treatment modality for lung cancer, however, radioresistance remains a fundamental barrier to attaining… (More)
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2009
2009
z-Leucinyl-leucinyl-norleucinal induces apoptosis of human glioblastoma tumor-initiating cells by proteasome inhibition and mitotic arrest response.
Gamma-secretase inhibitors have been proposed as drugs able to kill cancer cells by targeting the NOTCH pathway. Here, we… (More)
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2004
2004
Porphyromonas gingivalis induces receptor activator of NF-kappaB ligand expression in osteoblasts through the activator protein 1 pathway.
Porphyromonas gingivalis, an important periodontal pathogen, is closely associated with inflammatory alveolar bone resorption… (More)
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2003
2003
B overexpression in cardiomyocytes prevents NF-B translocation and provides cardioprotection in trauma
Carlson, Deborah L., D. Jean White, David L. Maass, Robin C. Nguyen, Brett Giroir, and Jureta W. Horton. I B overexpression in… (More)
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2002
2002
A proteasome inhibitor confers cardioprotection.
OBJECTIVE In several cell types, proteasome inhibitors like carbobenzoxyl-leucinyl-leucinyl-leucinal (MG132) induce the 72 kDa… (More)
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2002
2002
Intracellular mechanisms mediating the inhibition of apoB-containing lipoprotein synthesis and secretion in HepG2 cells by avasimibe (CI-1011), a novel acyl-coenzyme A: cholesterol acyltransferase…
We have studied the cellular and molecular mechanisms involved in the suppression of apoB secretion from HepG2 cells following… (More)
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2001
2001
Proteasomal activation mediates down-regulation of inositol 1,4,5-trisphosphate receptor and calcium mobilization in rat pancreatic islets.
Inositol 1,4,5-trisphosphate receptor (IP3R) protein levels in isolated rat pancreatic islets were investigated in response to… (More)
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2001
2001
Differentiation-dependent sensitivity to cell death induced in the developing retina by inhibitors of the ubiquitin-proteasome proteolytic pathway.
The effects of inhibitors of proteasome function were studied in the retina of developing rats. Explants from the retina of… (More)
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1999
1999
Depolarization regulates cyclin D1 degradation and neuronal apoptosis: a hypothesis about the role of the ubiquitin/proteasome signalling pathway.
Depolarization and subsequent calcium entry exert essential neuroprotective effects but the ultimate effector by which calcium… (More)
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1998
1998
Enhanced in vitro cytotoxicity and cytostasis of the combination of onconase with a proteasome inhibitor.
In proliferating cells the turnover rate of proteins responsible for regulation of the cell cycle progression, namely cyclins and… (More)
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