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MG 115

Known as: MG-115, MG115 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

carbobenzoxy-leucyl-leucyl-norvalinal

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
A Proteolytic Cascade Controls Lysosome Rupture and Necrotic Cell Death Mediated by Lysosome-Destabilizing Adjuvants
Recent studies have linked necrotic cell death and proteolysis of inflammatory proteins to the adaptive immune response mediated… 
2014
2014
Lamotrigine Attenuates Proteasome Inhibition-Induced Apoptosis by Suppressing the Activation of the Mitochondrial Pathway and the Caspase-8- and Bid-Dependent Pathways
Proteasome impairment has been shown to be involved in neuronal degeneration. Antiepileptic lamotrigine has been demonstrated to… 
Highly Cited
2007
Highly Cited
2007
Sperm proteasomes are responsible for the acrosome reaction and sperm penetration of the vitelline envelope during fertilization of the sea urchin Pseudocentrotus depressus.
2004
2004
Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells.
2004
2004
Proteasome inhibitors and their combination with antiandrogens: effects on apoptosis, cellular proliferation and viability of prostatic adenocarcinoma cell cultures
The 26S proteasome is a ubiquitin-dependent proteolytic system that has been implicated in the regulation of cell cycle… 
2003
2003
Effect of MG132, a proteasome inhibitor, on the expression of growth related oncogene protein-alpha in human umbilical vein endothelial cells.
2001
2001
Role of proteasomal degradation in the cell cycle-dependent regulation of DNA topoisomerase IIalpha expression.
Highly Cited
1998
Highly Cited
1998
Involvement of Heat Shock Protein 90 in the Degradation of Mutant Insulin Receptors by the Proteasome*
We previously reported three families with type A insulin-resistant syndrome who had mutations, either Asp1179 or Leu1193, in the… 
Highly Cited
1997
Highly Cited
1997
Detailed analysis of cell cycle kinetics upon proteasome inhibition.
We have studied specific effects of proteasome inhibition on cell cycle progression. To this end, the protease inhibitors MG115… 
1997
1997
The proteasome is an essential mediator of the activation of pre-MPF during starfish oocyte maturation.
Starfish oocyte maturation was blocked by the addition of 100 microM MG115, a potent proteasome inhibitor, whereas no inhibition… 
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