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capecitabine

Known as: Capecitabina, Capecitabin, Pentyl 1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate 
A fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively… 
National Institutes of Health

Related topics

Related topics

27 relations

Broader (1)

Antimetabolites, Antineoplastic
CAPOX RegimenCAPOX-Bevacizumab RegimenColorectal NeoplasmsDrug Allergy

Narrower (1)

Xeloda

Papers overview

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Highly Cited
2015
Highly Cited
2015
CEREBEL (EGF111438): A Phase III, Randomized, Open-Label Study of Lapatinib Plus Capecitabine Versus Trastuzumab Plus Capecitabine in Patients With Human Epidermal Growth Factor Receptor 2-Positive…
PURPOSE CEREBEL compared the incidence of CNS metastases as first site of relapse in patients with human epidermal growth factor… 
Highly Cited
2014
Highly Cited
2014
Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis: the New EPOC randomised controlled trial.
Highly Cited
2010
Highly Cited
2010
Pinnacle Point Cave 13B (Western Cape Province, South Africa) in context: The Cape Floral kingdom, shellfish, and modern human origins.
Highly Cited
2007
Highly Cited
2007
Predictors of tumor response and downstaging in patients who receive preoperative chemoradiation for rectal cancer
The objective of this study was to identify predictive factors for pathologic complete response and tumor downstaging after… 
Highly Cited
2005
Highly Cited
2005
Hydrolysis of Capecitabine to 5′-Deoxy-5-fluorocytidine by Human Carboxylesterases and Inhibition by Loperamide
Capecitabine is an oral prodrug of 5-fluorouracil that is indicated for the treatment of breast and colorectal cancers. A three… 
Highly Cited
2001
Highly Cited
2001
Rapid and recent origin of species richness in the Cape flora of South Africa
The Cape flora of South Africa grows in a continental area with many diverse and endemic species. We need to understand the… 
Highly Cited
2000
Highly Cited
2000
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis.
Ethionamide (ETA) is an important component of second-line therapy for the treatment of multidrug-resistant tuberculosis… 
Highly Cited
1998
Highly Cited
1998
Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts…
Capecitabine (N4-pentyloxycarbonyl-5'-deoxy-5-fluorocytidine) is a new fluoropyrimidine carbamate, which is converted to 5… 
Highly Cited
1997
Highly Cited
1997
Analytical energy dissipation models for low-power caches
We present detailed analytical models for estimating the energy dissipation in conventional caches as well as low energy cache… 
Review
1995
Review
1995
Two Late Pleistocene-Holocene Archaeological Depositories from the Southern Cape, South Africa
This paper reviews research at two sites in the southern Cape, South Afnca that together span the last 125 ka: Boomplaas and… 
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