capecitabine

Known as: Capecitabina, Capecitabin, Pentyl 1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate 
A fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
BACKGROUND D2 gastrectomy is recommended in US and European guidelines, and is preferred in east Asia, for patients with… (More)
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Highly Cited
2012
Highly Cited
2012
PURPOSE The ARTIST (Adjuvant Chemoradiation Therapy in Stomach Cancer) trial was the first study to our knowledge to investigate… (More)
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Highly Cited
2010
Highly Cited
2010
n engl j med 362;9 nejm.org march 4, 2010 858 The authors reply: We agree with Hancock that the electrocardiogram presented in… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Trastuzumab, a monoclonal antibody against human epidermal growth factor receptor 2 (HER2; also known as ERBB2), was… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND To compare capecitabine/cisplatin with 5-fluorouracil/cisplatin as first-line treatment for advanced gastric cancer… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE To evaluate whether capecitabine plus oxaliplatin (XELOX) is noninferior to fluorouracil. folinic acid, and oxaliplatin… (More)
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Highly Cited
2002
Highly Cited
2002
PURPOSE Docetaxel and capecitabine, a tumor-activated oral fluoropyrimidine, show high single-agent efficacy in metastatic breast… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE To compare the response rate, efficacy parameters, and toxicity profile of oral capecitabine with bolus intravenous (IV… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE To compare the efficacy and safety of orally administered capecitabine (Xeloda; Roche Laboratories, Inc, Nutley, NJ), a… (More)
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Highly Cited
1998
Highly Cited
1998
Capecitabine (N4-pentyloxycarbonyl-5'-deoxy-5-fluorocytidine) is a novel oral fluoropyrimidine carbamate, which is converted to 5… (More)
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