Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

candoxatrilat

Known as: 4-((2-carboxy-3-(2-methoxyethoxy)propyl)-1-cyclopentanecarbonylamino)-1-cyclohexanecarboxylic acid, Cyclohexanecarboxylic acid, 4-(((1-(2-carboxy-3-(2-methoxyethoxy)propyl)cyclopentyl)carbonyl)amino)-, cis-(+-)- 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Stimulation of cardiomyocyte guanosine 3',5'-cyclic monophosphate (cyclic GMP) via endothelial-derived nitric oxide (NO) is an… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
BACKGROUND Neutral endopeptidase 24.11 (NEP) is a metalloprotease that is localized in the greatest abundance in the kidney and… Expand
  • table 1
  • figure 1
  • table 2
  • figure 2
Is this relevant?
Highly Cited
1998
Highly Cited
1998
BACKGROUND Neutral endopeptidase (NEP) degrades vasoactive peptides, including the natriuretic peptides, angiotensin II, and… Expand
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 3
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Adrenomedullin (ADM) is a potent renal vasodilating and natriuretic peptide possessing a six amino acid disulfide ring. Neutral… Expand
Is this relevant?
1998
1998
Adrenomedullin (ADM) is a potent renal vasodilating and natriuretic peptide possessing a six amino acid disulfide ring. Neutral… Expand
Is this relevant?
1997
1997
1. Candoxatrilat, an active neutral endopeptidase inhibitor, was released rapidly from the inactive prodrug candoxatril in vivo… Expand
Is this relevant?
1997
1997
C-type natriuretic peptide (CNP) is a newly described 22-amino acid peptide of endothelial and renal cell origin with selective… Expand
Is this relevant?
1995
1995
OBJECTIVES Our primary objective was to compare the effects of three different doses of candoxatrilat with the effects of placebo… Expand
Is this relevant?
1995
1995
We studied six healthy male subjects in a randomized, placebo-controlled, single-blind fashion to determine the comparative… Expand
Is this relevant?
Highly Cited
1992
Highly Cited
1992
BackgroundThe purpose of this study was to investigate the therapeutic potential of prolonged inhibition of atrial natriuretic… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?