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calphostin C

Known as: Carbonic acid, 2-(12-(2-(benzoyloxy)propyl)-3,10-dihydro-4,9-dihydroxy-2,6,7,11-tetramethoxy-3,10-dioxo-1-perylenyl)-1-methylethyl 4-hydroxyphenyl ester 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Antibiotics, AntineoplasticEnzyme InhibitorsNaphthalenes

Narrower (1)

UCN 1028 C

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
PKC inhibition is involved in trichosanthin-induced apoptosis in human chronic myeloid leukemia cell line K562.
Highly Cited
2006
Highly Cited
2006
Roles of PKC, PI3K and JNK in multiple transduction of CCN2/CTGF signals in chondrocytes.
2004
2004
Tissue transglutaminase triggers oligomerization and activation of dual leucine zipper-bearing kinase in calphostin C-treated cells to facilitate apoptosis
AbstractAlthough tissue transglutaminase (tTG) has been recognized as a mediator of apoptosis in various experimental models… 
2004
2004
Calphostin-C Induction of Vascular Smooth Muscle Cell Apoptosis Proceeds through Phospholipase D and Microtubule Inhibition*
Calphostin-C, a protein kinase C inhibitor, induces apoptosis of cultured vascular smooth muscle cells. However, the mechanisms… 
2000
2000
Calphostin C-mediated translocation and integration of Bax into mitochondria induces cytochrome c release before mitochondrial dysfunction
Calphostin C-mediated apoptosis in glioma cells was reported previously to be associated with down-regulation of Bcl-2 and Bcl-xL… 
1999
1999
Signal transduction in spontaneous myogenic tone in isolated arterioles from rat skeletal muscle.
Highly Cited
1994
Highly Cited
1994
Preconditioning of isolated rabbit cardiomyocytes: induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C, a protein kinase C inhibitor.
OBJECTIVE The aim was to determine if isolated rabbit cardiomyocytes could be preconditioned. METHODS Cardiomyocytes isolated… 
Highly Cited
1994
Highly Cited
1994
Apoptosis of vascular smooth muscle cells. Protein kinase C and oncoprotein Bcl-2 are involved in regulation of apoptosis in non-transformed rat vascular smooth muscle cells.
We examined the effect of several inhibitors/activators of various protein kinases on the proliferation and apoptosis of… 
1993
1993
Sustained Recovery of Na+-K+-ATPase Activity in Sciatic Nerve of Diabetic Mice by Administration of H7 or Calphostin C, Inhibitors of PKC
We have previously shown that intraperitoneal injection of H-7, an inhibitor of PKC, restores completely the activity of Na+-K… 
Highly Cited
1992
Highly Cited
1992
Effects of inhibitors of protein kinase C and calpain in experimental delayed cerebral vasospasm.
Vasospasm was produced in adult mongrel dogs by a two-hemorrhage method, and the spastic basilar arteries were exposed via the… 
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