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cGMP-Dependent Protein Kinase Ialpha

Known as: PKGIalpha, cGK-Ialpha, cGMP Dependent Protein Kinase Ialpha 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2010
012320042010

Related topics

Related topics

1 relation

Broader (1)

Cyclic GMP-Dependent Protein Kinase Type I

Related mentions per year

Related mentions per year

2002-2016
20002005201020152020
cGMP-Dependent Protein Kinase Ialpha
Cyclic GMP-Dependent Protein Kinase Type I

Papers overview

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2010
2010
Adenosine analogue-oligo-arginine conjugates (ARCs) serve as high-affinity inhibitors and fluorescence probes of type I cGMP-dependent protein kinase (PKGIalpha).
INTRODUCTION Type I cGMP-dependent protein kinase (PKGIalpha) belongs to the family of cyclic nucleotide-dependent protein… (More)
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2010
2010
Aromatic L-amino acid decarboxylase phosphorylation and activation by PKGIalpha in vitro.
Brain aromatic L-amino acid decarboxylase (AAAD) is subject to regulation, and phosphorylation might be involved in the short… (More)
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2009
2009
Transnitrosylating nitric oxide species directly activate type I protein kinase A, providing a novel adenylate cyclase-independent cross-talk to beta-adrenergic-like signaling.
The transnitrosylating nitric oxide (NO) donor nitrocysteine (CysNO) induced a disulfide bond between the two regulatory RI… (More)
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2008
2008
High blood pressure arising from a defect in vascular function.
Hypertension, a major cardiovascular risk factor and cause of mortality worldwide, is thought to arise from primary renal… (More)
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2007
2007
Protein kinase G phosphorylates Cav1.2 alpha1c and beta2 subunits.
Voltage-dependent Ca(2+) channel function (Ca(v)1.2, L-type Ca(2+) channel) is required for cardiac excitation-contraction (E-C… (More)
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2007
2007
MYPT1 mutants demonstrate the importance of aa 888-928 for the interaction with PKGIalpha.
During nitric oxide signaling, type Ialpha cGMP-dependent protein kinase (PKGIalpha) activates myosin light chain (MLC… (More)
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Highly Cited
2006
Highly Cited
2006
Cyclic GMP-dependent protein kinase Ialpha attenuates necrosis and apoptosis following ischemia/reoxygenation in adult cardiomyocyte.
Cyclic GMP-dependent protein kinases protein kinase G (PKG) Ialpha and PKGIbeta are major mediators of cGMP signaling in the… (More)
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2006
2006
Isolated regulatory domains of cGMP-dependent protein kinase Ialpha and Ibeta retain dimerization and native cGMP-binding properties and undergo isoform-specific conformational changes.
Molecular mechanisms that provide for cGMP activation of cGMP-dependent protein kinase (PKG) are unknown. PKGs are dimeric; each… (More)
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2006
2006
Cyclic GMP-dependent protein kinase Ialpha inhibits thrombin receptor-mediated calcium mobilization in vascular smooth muscle cells.
Vascular smooth muscle contractile state is regulated by intracellular calcium levels. Nitric oxide causes vascular relaxation by… (More)
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2005
2005
cGMP-phosphodiesterase antagonists inhibit Ca2+-influx in Dictyostelium discoideum and bovine cyclic-nucleotide-gated-channel.
We used antagonists of cGMP-phosphodiesterases to examine the role of cGMP for light-scattering oscillations and cAMP-induced Ca… (More)
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