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Cyclic GMP-Dependent Protein Kinase Type I

Known as: cGMP-Dependent Protein Kinase I, cGMP Dependent Protein Kinase I, Cyclic GMP-Dependent Protein Kinase Type I [Chemical/Ingredient] 
A cyclic GMP-dependent protein kinase subtype that is expressed in SMOOTH MUSCLE tissues and plays a role in regulation of smooth muscle contraction… Expand
National Institutes of Health

Related topics

Related topics

11 relations
In BloodPRKG1 geneProcess of secretionantagonists & inhibitors
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Narrower (3)

PRKG1 protein, humancGMP-Dependent Protein Kinase IalphacGMP-Dependent Protein Kinase Ibeta

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Oxidative Stress-Activated NHE1 Is Involved in High Glucose-Induced Apoptosis in Renal Tubular Epithelial Cells
Purpose Diabetic nephropathy (DN) is a prevalent chronic microvascular complication of diabetes mellitus involving disturbances… Expand
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2012
2012
Structural and functional analysis of cGMP dependent protein kinase I (cGKI) and LIM kinase 1 (LIMK1) engaged in BMP signaling crosstalk
 
2011
2011
Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5)
The clitoris contributes to the normal female sexual response cycle. A significance of cyclic guanosine monophosphate (GMP) has… Expand
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2011
2011
Activation of cGMP-dependent protein kinase Iα and cAMP-dependent protein kinase A isoforms by cyclic nucleotides
cAMP and cGMP are second messengers that play important roles in intracellular signal transduction of various external stimuli… Expand
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2009
2009
Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle.
cGMP-dependent protein kinase I (cGKI) induces relaxation of smooth muscle via several pathways that include inhibition of… Expand
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Highly Cited
2007
Highly Cited
2007
Rescue of cGMP Kinase I Knockout Mice by Smooth Muscle–Specific Expression of Either Isozyme
Smooth muscle expresses the I&agr; and the I&bgr; isoforms of cGMP-dependent protein kinase I (cGKI). Inactivation of the murine… Expand
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Review
2007
Review
2007
cGMP-dependent protein kinase I and smooth muscle relaxation: a tale of two isoforms.
  • H. Surks
  • Circulation research
  • 2007
    • Corpus ID: 26292545
See related article, pages 1096–1103 The maintenance of vascular tone is central to the regulation of blood pressure and tissue… Expand
2005
2005
Abnormal neocortical development in mice lacking cGMP-dependent protein kinase I.
Cyclic GMP-dependent protein kinase type I (cGKI) is a key signaling intermediate important for synaptic potentiation in the… Expand
Highly Cited
2000
Highly Cited
2000
Functional characteristics of urinary tract smooth muscles in mice lacking cGMP protein kinase type I.
Nitric oxide (NO)-mediated smooth muscle relaxation is mediated by cGMP through activation of cGMP-dependent protein kinase I… Expand
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Highly Cited
1996
Highly Cited
1996
Nitric oxide synthase and cyclic GMP-dependent protein kinase concentrated at the neuromuscular endplate
Nitric oxide mediates diverse functions in development and physiology of vertebrate skeletal muscle. Neuronal type nitric oxide… Expand
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