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Cyclic GMP-Dependent Protein Kinase Type I

Known as: cGMP-Dependent Protein Kinase I, cGMP Dependent Protein Kinase I, Cyclic GMP-Dependent Protein Kinase Type I [Chemical/Ingredient] 
A cyclic GMP-dependent protein kinase subtype that is expressed in SMOOTH MUSCLE tissues and plays a role in regulation of smooth muscle contraction… 
National Institutes of Health

Related topics

Related topics

11 relations
In BloodPRKG1 geneProcess of secretionantagonists & inhibitors

Narrower (3)

PRKG1 protein, humancGMP-Dependent Protein Kinase IalphacGMP-Dependent Protein Kinase Ibeta

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Oxidative Stress-Activated NHE1 Is Involved in High Glucose-Induced Apoptosis in Renal Tubular Epithelial Cells
Purpose Diabetic nephropathy (DN) is a prevalent chronic microvascular complication of diabetes mellitus involving disturbances… 
2012
2012
Structural and functional analysis of cGMP dependent protein kinase I (cGKI) and LIM kinase 1 (LIMK1) engaged in BMP signaling crosstalk
2011
2011
Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5)
The clitoris contributes to the normal female sexual response cycle. A significance of cyclic guanosine monophosphate (GMP) has… 
2011
2011
Activation of cGMP-dependent protein kinase Iα and cAMP-dependent protein kinase A isoforms by cyclic nucleotides
cAMP and cGMP are second messengers that play important roles in intracellular signal transduction of various external stimuli… 
2009
2009
Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle.
cGMP-dependent protein kinase I (cGKI) induces relaxation of smooth muscle via several pathways that include inhibition of… 
Highly Cited
2007
Highly Cited
2007
Rescue of cGMP Kinase I Knockout Mice by Smooth Muscle–Specific Expression of Either Isozyme
Smooth muscle expresses the I&agr; and the I&bgr; isoforms of cGMP-dependent protein kinase I (cGKI). Inactivation of the murine… 
Review
2007
Review
2007
cGMP-dependent protein kinase I and smooth muscle relaxation: a tale of two isoforms.
  • H. Surks
  • Circulation Research
  • 2007
  • Corpus ID: 26292545
See related article, pages 1096–1103 The maintenance of vascular tone is central to the regulation of blood pressure and tissue… 
2005
2005
Abnormal neocortical development in mice lacking cGMP-dependent protein kinase I.
Highly Cited
2000
Highly Cited
2000
Functional characteristics of urinary tract smooth muscles in mice lacking cGMP protein kinase type I.
Nitric oxide (NO)-mediated smooth muscle relaxation is mediated by cGMP through activation of cGMP-dependent protein kinase I… 
Highly Cited
1996
Highly Cited
1996
Nitric oxide synthase and cyclic GMP-dependent protein kinase concentrated at the neuromuscular endplate
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