FAQ

Cyclic GMP-Dependent Protein Kinase Type I

Known as: cGMP-Dependent Protein Kinase I, cGMP Dependent Protein Kinase I, Cyclic GMP-Dependent Protein Kinase Type I [Chemical/Ingredient] 
A cyclic GMP-dependent protein kinase subtype that is expressed in SMOOTH MUSCLE tissues and plays a role in regulation of smooth muscle contraction… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2013
0119972013

Related topics

Related topics

12 relations
In BloodPRKG1 geneProcess of secretionantagonists & inhibitors
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Narrower (4)

PRKG1 protein, humanPrkg1 protein, mousecGMP-Dependent Protein Kinase IalphacGMP-Dependent Protein Kinase Ibeta

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Cyclic GMP-Dependent Protein Kinase Type I
physiological aspects
In Blood
chemical synthesis
standards characteristics
Process of secretion

Papers overview

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2013
2013
Evidence for functional coupling of cGMP/cGKI signalling and TRPC channels in endothelium but not in vascular smooth muscle
Background Signaling via cGMP-dependent protein kinase I (cGKI) is the major pathway in vascular smooth muscle (SM), by which… (More)
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2008
2008
cGMP produced by NO-sensitive guanylyl cyclase essentially contributes to inflammatory and neuropathic pain by using targets different from cGMP-dependent protein kinase I.
A large body of evidence indicates that the release of nitric oxide (NO) is crucial for the central sensitization of pain… (More)
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2008
2008
Cysteine-rich protein 2, a novel downstream effector of cGMP/cGMP-dependent protein kinase I-mediated persistent inflammatory pain.
The cGMP/cGMP-dependent protein kinase I (cGKI) signaling pathway plays an important role in spinal nociceptive processing… (More)
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2008
2008
Probing the interaction between the coiled coil leucine zipper of cGMP-dependent protein kinase Ialpha and the C terminus of the myosin binding subunit of the myosin light chain phosphatase.
Nitric oxide and nitrovasodilators induce vascular smooth muscle cell relaxation in part by cGMP-dependent protein kinase I (PKG… (More)
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Review
2007
Review
2007
cGMP-dependent protein kinase I and smooth muscle relaxation: a tale of two isoforms.
The maintenance of vascular tone is central to the regulation of blood pressure and tissue perfusion and plays a role in the… (More)
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2002
2002
Functional reconstitution of vascular smooth muscle cells with cGMP-dependent protein kinase I isoforms.
The cGMP-dependent protein kinase type I (cGKI) is a major mediator of NO/cGMP-induced vasorelaxation. Smooth muscle expresses… (More)
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1997
1997
Nitric oxide synthase and cyclic GMP-dependent protein kinase concentrated at the neuromuscular endplate.
Nitric oxide mediates diverse functions in development and physiology of vertebrate skeletal muscle. Neuronal type nitric oxide… (More)
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