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Cyclic GMP-Dependent Protein Kinase Type I

Known as: cGMP-Dependent Protein Kinase I, cGMP Dependent Protein Kinase I, Cyclic GMP-Dependent Protein Kinase Type I [Chemical/Ingredient] 
A cyclic GMP-dependent protein kinase subtype that is expressed in SMOOTH MUSCLE tissues and plays a role in regulation of smooth muscle contraction… Expand
National Institutes of Health

Related topics

Related topics

11 relations
In BloodPRKG1 geneProcess of secretionantagonists & inhibitors
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Narrower (3)

PRKG1 protein, humancGMP-Dependent Protein Kinase IalphacGMP-Dependent Protein Kinase Ibeta

Papers overview

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2016
2016
Oxidative Stress-Activated NHE1 Is Involved in High Glucose-Induced Apoptosis in Renal Tubular Epithelial Cells
PURPOSE Diabetic nephropathy (DN) is a prevalent chronic microvascular complication of diabetes mellitus involving disturbances… Expand
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2012
2012
Structural and functional analysis of cGMP dependent protein kinase I (cGKI)and LIM kinase 1 (LIMK1) engaged in BMP signaling crosstalk
 
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2011
2011
Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5)
The clitoris contributes to the normal female sexual response cycle. A significance of cyclic guanosine monophosphate (GMP) has… Expand
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2011
2011
Activation of cGMP-dependent protein kinase Iα and cAMP-dependent protein kinase A isoforms by cyclic nucleotides
cAMP and cGMP are second messengers that play important roles in intracellular signal transduction of various external stimuli… Expand
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2010
2010
Two Isoforms cGMP-Dependent Protein Kinase I and Smooth Muscle Relaxation: A Tale of
 
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2009
2009
Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle.
cGMP-dependent protein kinase I (cGKI) induces relaxation of smooth muscle via several pathways that include inhibition of… Expand
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Highly Cited
2007
Highly Cited
2007
Rescue of cGMP kinase I knockout mice by smooth muscle specific expression of either isozyme.
Smooth muscle expresses the Ialpha and the Ibeta isoforms of cGMP-dependent protein kinase I (cGKI). Inactivation of the murine… Expand
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2005
2005
Abnormal neocortical development in mice lacking cGMP-dependent protein kinase I.
Cyclic GMP-dependent protein kinase type I (cGKI) is a key signaling intermediate important for synaptic potentiation in the… Expand
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2000
2000
Functional characteristics of urinary tract smooth muscles in mice lacking cGMP protein kinase type I.
Nitric oxide (NO)-mediated smooth muscle relaxation is mediated by cGMP through activation of cGMP-dependent protein kinase I… Expand
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1996
1996
Nitric oxide synthase and cyclic GMP-dependent protein kinase concentrated at the neuromuscular endplate
Nitric oxide mediates diverse functions in development and physiology of vertebrate skeletal muscle. Neuronal type nitric oxide… Expand
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