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Cyclic GMP-Dependent Protein Kinase Type I
Known as:
cGMP-Dependent Protein Kinase I
, cGMP Dependent Protein Kinase I
, Cyclic GMP-Dependent Protein Kinase Type I [Chemical/Ingredient]
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A cyclic GMP-dependent protein kinase subtype that is expressed in SMOOTH MUSCLE tissues and plays a role in regulation of smooth muscle contraction…
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National Institutes of Health
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Related topics
Related topics
11 relations
In Blood
PRKG1 gene
Process of secretion
antagonists & inhibitors
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Narrower (3)
PRKG1 protein, human
cGMP-Dependent Protein Kinase Ialpha
cGMP-Dependent Protein Kinase Ibeta
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Oxidative Stress-Activated NHE1 Is Involved in High Glucose-Induced Apoptosis in Renal Tubular Epithelial Cells
Yiqing Wu
,
Min Zhang
,
Rui Liu
,
Chunjie Zhao
Yonsei medical journal
2016
Corpus ID: 18034324
Purpose Diabetic nephropathy (DN) is a prevalent chronic microvascular complication of diabetes mellitus involving disturbances…
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2012
2012
Structural and functional analysis of cGMP dependent protein kinase I (cGKI) and LIM kinase 1 (LIMK1) engaged in BMP signaling crosstalk
A. Beltrami
2012
Corpus ID: 97893288
2011
2011
Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5)
S. Ückert
,
M. Oelke
,
K. Albrecht
,
D. Breitmeier
,
M. Kuczyk
,
P. Hedlund
International journal of impotence research
2011
Corpus ID: 8094839
The clitoris contributes to the normal female sexual response cycle. A significance of cyclic guanosine monophosphate (GMP) has…
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2011
2011
Activation of cGMP-dependent protein kinase Iα and cAMP-dependent protein kinase A isoforms by cyclic nucleotides
Sabine Wolter
,
M. Golombek
,
Andreas Hammerschmidt
,
F. Schwede
,
H. Genieser
,
R. Seifert
BMC Pharmacology
2011
Corpus ID: 4027696
cAMP and cGMP are second messengers that play important roles in intracellular signal transduction of various external stimuli…
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2009
2009
Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle.
E. Frei
,
Maria Huster
,
Petra Smital
,
J. Schlossmann
,
F. Hofmann
,
J. Wegener
American Journal of Physiology - Gastrointestinal…
2009
Corpus ID: 12118714
cGMP-dependent protein kinase I (cGKI) induces relaxation of smooth muscle via several pathways that include inhibition of…
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Highly Cited
2007
Highly Cited
2007
Rescue of cGMP Kinase I Knockout Mice by Smooth Muscle–Specific Expression of Either Isozyme
Silke Weber
,
Dominik Bernhard
,
+8 authors
R. Feil
Circulation Research
2007
Corpus ID: 43914365
Smooth muscle expresses the I&agr; and the I&bgr; isoforms of cGMP-dependent protein kinase I (cGKI). Inactivation of the murine…
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Review
2007
Review
2007
cGMP-dependent protein kinase I and smooth muscle relaxation: a tale of two isoforms.
H. Surks
Circulation Research
2007
Corpus ID: 26292545
See related article, pages 1096–1103 The maintenance of vascular tone is central to the regulation of blood pressure and tissue…
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2005
2005
Abnormal neocortical development in mice lacking cGMP-dependent protein kinase I.
G. Demyanenko
,
A. Halberstadt
,
K. Pryzwansky
,
C. Werner
,
F. Hofmann
,
P. Maness
Brain research. Developmental brain research
2005
Corpus ID: 25556075
Highly Cited
2000
Highly Cited
2000
Functional characteristics of urinary tract smooth muscles in mice lacking cGMP protein kinase type I.
K. Persson
,
R. Pandita
,
+4 authors
K. Andersson
American Journal of Physiology. Regulatory…
2000
Corpus ID: 2471656
Nitric oxide (NO)-mediated smooth muscle relaxation is mediated by cGMP through activation of cGMP-dependent protein kinase I…
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Highly Cited
1996
Highly Cited
1996
Nitric oxide synthase and cyclic GMP-dependent protein kinase concentrated at the neuromuscular endplate
D. Chao
,
F. Silvagno
,
H. Xia
,
T. Cornwell
,
T. Lincoln
,
D. Bredt
Neuroscience
1996
Corpus ID: 21197605
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