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brodimoprim

Known as: 2,4-diamino-5-(4-bromo-3,5-dimethoxybenzyl)pyrimidine 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Anti-Infective AgentsEnzyme InhibitorsFolic Acid AntagonistsTrimethoprim
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Establishment of a liquid chromatographic/mass spectrometry method for quantification of tetrandrine in rat plasma and its application to pharmacokinetic study.
2008
2008
Liquid chromatography/tandem mass spectrometry method for simultaneous evaluation of activities of five cytochrome P450s using a five-drug cocktail and application to cytochrome P450 phenotyping…
1995
1995
Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase.
Two-dimensional (2D) double-quantum-filtered correlation spectroscopy (DQF-COSY), total correlation spectroscopy (TOCSY), nuclear… 
Review
1995
Review
1995
Brodimoprim, a new bacterial dihydrofolate reductase inhibitor: a minireview.
This brief review article synthesizes the principal literature regarding the clinical status of co-trimoxazole compared to… 
1995
1995
Influence of subinhibitory concentrations of brodimoprim and trimethoprim on the adhesiveness, hydrophobicity, hemagglutination and motility of Escherichia coli.
In the present study the ability of subinhibitory concentrations (sub-MICs) of brodimoprim (a new 2,4-dimethoxybenzylpyrimidine… 
Review
1993
Review
1993
Comparative antibacterial spectrum of trimethoprim and brodimoprim.
Brodimoprim is a new 2,4-diaminobenzylpyrimidine that selectively inhibits bacterial and resistance plasmid dihydrofolate… 
1993
1993
Brodimoprim in acute respiratory tract infections.
Brodimoprim was studied in the treatment of acute respiratory tract infections in hospitalized, basically healthy, military… 
Review
1993
Review
1993
Brodimoprim: therapeutic efficacy and safety in the treatment of bacterial infections.
The clinical efficacy and safety of brodimoprim has been studied by numerous investigators. In the trials reviewed 2291 cases… 
1984
1984
A 1H NMR study of the interactions and conformations of rationally designed brodimoprim analogues in complexes with Lactobacillus casei dihydrofolate reductase.
A consideration of the detailed structural information available from X-ray crystallographic and NMR studies on complexes of… 
1984
1984
Properties of brodimoprim as an inhibitor of dihydrofolate reductases.
Based on both IC50 and Ki values, brodimoprim (BDP) was often found to be two- to threefold more effective than trimethoprim (TMP… 
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