brivanib

Known as: (R)-1-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5- methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan- 2-ol 
A pyrrolotriazine-based compound and an inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) with potential antineoplastic activity… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2018
0102020062018

Papers overview

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2014
2014
UNLABELLED Transarterial chemoembolization (TACE) is the current standard of treatment for unresectable intermediate-stage… (More)
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Highly Cited
2013
Highly Cited
2013
PURPOSE Brivanib is a dual inhibitor of vascular-endothelial growth factor and fibroblast growth factor receptors that are… (More)
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Highly Cited
2013
Highly Cited
2013
PURPOSE Brivanib is a selective dual inhibitor of vascular endothelial growth factor and fibroblast growth factor receptors… (More)
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Highly Cited
2012
Highly Cited
2012
PURPOSE Brivanib, a selective dual inhibitor of fibroblast growth factor and VEGF signaling, has recently been shown to have… (More)
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2011
2011
PURPOSE Preclinical trials of a mouse model of pancreatic neuroendocrine tumors (PNET) were conducted to determine whether dual… (More)
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2010
2010
The goal of this study was to evaluate the pharmacokinetics, mass balance, metabolism, routes and extent of elimination, and… (More)
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2009
2009
Fibroblast growth factor receptor-1 (FGFR-1) is amplified in 10% of human breast cancers. The goal of this study was to test the… (More)
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2009
2009
4577 Background: Brivanib is an orally available dual inhibitor of vascular endothelial growth factor and fibroblast growth… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Hepatocellular carcinoma (HCC) is the fifth most common primary neoplasm; surgery is the only curative option but 5-year… (More)
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2006
2006
A series of substituted 4-(4-fluoro-1H-indol-5-yloxy)pyrrolo[2,1-f][1,2,4]triazine-based inhibitors of vascular endothelial… (More)
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