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brivanib alaninate

The alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
PURPOSE The antiepidermal growth factor receptor monoclonal antibody cetuximab has improved survival in patients with metastatic… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND This study was designed to determine the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of brivanib in… Expand
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Highly Cited
2010
Highly Cited
2010
Tumor angiogenesis is a complex and tightly regulated network mediated by various proangiogenic factors. The fibroblast growth… Expand
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2010
2010
PURPOSE Tamoxifen, a selective oestrogen receptor modulator (SERM), and brivanib alaninate, a vascular endothelial growth factor… Expand
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Highly Cited
2009
Highly Cited
2009
Fibroblast growth factor receptor-1 (FGFR-1) is amplified in 10% of human breast cancers. The goal of this study was to test the… Expand
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2009
2009
PurposeBrivanib alaninate is a prodrug of brivanib (BMS-540215), a potent oral VEGFR-2 inhibitor and is currently in development… Expand
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Highly Cited
2008
Highly Cited
2008
Purpose: Hepatocellular carcinoma (HCC) is the fifth most common primary neoplasm; surgery is the only curative option but 5-year… Expand
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Highly Cited
2008
Highly Cited
2008
A series of amino acid ester prodrugs of the dual VEGFR-2/FGFR-1 kinase inhibitor 1 (BMS-540215) was prepared in an effort to… Expand
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2007
2007
The process of neovascularization from preexisting blood vessels, referred to as angiogenesis, plays a critical role in both… Expand
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2005
2005
  • Sumita Roy, J. Dey
  • Langmuir : the ACS journal of surfaces and…
  • 2005
  • Corpus ID: 19910993
Two N-acyl amino acid surfactants, sodium N-(11-acrylamidoundecanoyl)-glycinate (SAUG) and L-alaninate (SAUA), were synthesized… Expand
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