bisnortilidine

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2017
012319782017

Papers overview

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2012
2012
Tilidine exhibits the highest consumption of opioids in Germany. The prodrug is hepatically metabolised in a sequential N… (More)
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2012
2012
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT The analgesic activity of tilidine is mediated by its active metabolite, nortilidine… (More)
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2011
2011
The opioid tilidine is a prodrug which is hepatically metabolized to active nortilidine and bisnortilidine. Due to the increasing… (More)
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2007
2007
Hair testing procedures allow a cumulative reflection of long-term drug abuse and are useful as a test for compliance in clinical… (More)
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2007
2007
The objective of the present study was to evaluate the pharmacokinetics of tilidine (CAS 20380-58-9), naloxone (CAS 465-65-6) and… (More)
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2006
2006
A fully validated liquid chromatographic procedure coupled with electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS… (More)
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2002
2002
The disposition of nortildine, the active metabolite of the synthetic opioid drug tilidine, was investigated in healthy… (More)
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2001
2001
The aim of the present study was to investigate the pharmacokinetics of tilidine and its metabolites during the dialysis… (More)
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1989
1989
Tilidine is a prodrug from which the active metabolite nortilidine is formed by demethylation. The pharmacokinetics of tilidine… (More)
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1978
1978
The analgesic effect of tilidine in rats is completely antagonized by the narcotic antagonist naloxone. Radioreceptor assays… (More)
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