bis(tri-n-butyltin)oxide

The biocide and environmental pollutant bis(tri-n-butyltin)oxide (TBTO) causes thymus atrophy in rodents. Whether the depletion… (More)

In this report the evaluation of a safety factor is assessed, according to the decision tree suggested by Renwick (1991a,b), to… (More)

Previous studies in the rat have shown that bis(tri-n-butyltin) oxide (TBTO), used as a biocide, was immunotoxic at dose levels… (More)

In order to characterise the mechanism of cytotoxicity of the immunotoxic organotin compound bis(tri-n-butyltin)oxide (TBTO) to… (More)

In a 106-wk toxicity and carcinogenicity study, groups of 60 male and 60 female weanling Wistar rats were fed 0, 0.5, or 50 mg… (More)

To investigate whether immune function suppression observed in an earlier study after short-term bis(tri-n-butyltin)oxide (TBTO… (More)

The respiratory tract is a major route of exposure to noxious agents as well as pathogens such as viruses. Natural killer (NK… (More)

Male and female Wistar rats were fed bis(tri-n-butyltin)oxide (TBTO) at 0, 5, 20, 80, or 320 mg/kg diet for 4 weeks. Clinical… (More)

To evaluate the functional significance of bis(tri-n-butyltin)oxide (TBTO)-induced thymus atrophy, lymphocyte depletion in spleen… (More)

A total of 160 Sprague-Dawley rats averaging in body weight, were used for histopathological and biochemical studies of toxicity… (More)