bicellular tight junction assembly

Known as: tight junction formation 
The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Intestinal barrier function is important for preserving health, as a compromised barrier allows antigen entry and can induce… (More)
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Highly Cited
2008
Highly Cited
2008
Transforming growth factor beta (TGF-beta) signaling facilitates metastasis in advanced malignancy. While a number of protein… (More)
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Highly Cited
2005
Highly Cited
2005
Claudin proteins form a large family of integral membrane proteins crucial for tight junction formation and function. Our… (More)
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Highly Cited
2005
Highly Cited
2005
Recent studies have revealed an important role for tight junction protein complexes in epithelial cell polarity. One of these… (More)
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Highly Cited
2005
Highly Cited
2005
The activity of Rho GTPases is carefully timed to control epithelial proliferation and differentiation. RhoA is downregulated… (More)
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Highly Cited
2003
Highly Cited
2003
Crumbs is an apical transmembrane protein crucial for epithelial morphogenesis in Drosophila melanogaster embryos. A protein with… (More)
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Highly Cited
2003
Highly Cited
2003
The blood-brain barrier (BBB) is essential for maintaining brain homeostasis and low permeability. BBB maintenance is important… (More)
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Highly Cited
2002
Highly Cited
2002
The mammalian protein ASIP/PAR-3 interacts with atypical protein kinase C isotypes (aPKC) and shows overall sequence similarity… (More)
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Highly Cited
1993
Highly Cited
1993
We previously identified a 220-kD constitutive protein of the plasma membrane undercoat which colocalizes at the… (More)
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Highly Cited
1982
Highly Cited
1982
We examine here the proposition that membrane lipids1–4, rather than intrinsic membrane proteins5–7, are the principal structural… (More)
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