negative regulation of bicellular tight junction assembly

Known as: negative regulation of tight junction formation, downregulation of tight junction assembly, down-regulation of tight junction formation 
Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly. [GO_REF:0000058, GOC:jz, GOC:TermGenie, PMID… (More)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Butyrate, one of the SCFA, promotes the development of the intestinal barrier. However, the molecular mechanisms underlying the… (More)
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Review
2006
Review
2006
The tight junction is an intracellular junctional structure that mediates adhesion between epithelial cells and is required for… (More)
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Highly Cited
2005
Highly Cited
2005
The par (partitioning-defective) genes express a set of conserved proteins that function in polarization and asymmetric cell… (More)
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Highly Cited
2003
Highly Cited
2003
Snail is a transcription repressor that plays a central role in the epithelium-mesenchyme transition (EMT), by which epithelial… (More)
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Highly Cited
2003
Highly Cited
2003
Tight junctions help establish polarity in mammalian epithelia by forming a physical barrier that separates apical and… (More)
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Highly Cited
2000
Highly Cited
2000
PAR (partitioning-defective) proteins, which were first identified in the nematode Caenorhabditis elegans, are essential for… (More)
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Highly Cited
2000
Highly Cited
2000
Epithelial cells form a highly selective barrier and line many organs. The epithelial barrier is maintained by closely apposed… (More)
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Highly Cited
2000
Highly Cited
2000
Junctional adhesion molecule (JAM) is an integral membrane protein that has been reported to colocalize with the tight junction… (More)
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Highly Cited
1997
Highly Cited
1997
Occludin is an integral membrane protein localizing at tight junctions in epithelial and endothelial cells. Occludin from… (More)
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Review
1987
Review
1987
The zonula occludens (ZO), also referred to as the tight junction, forms the barrier to the diffusion of molecules and ions… (More)
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