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beta2-adrenergic receptor activity

Known as: beta2 adrenoceptor 
Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Vilanterol trifenatate, a novel inhaled long-acting beta2 adrenoceptor agonist, is well tolerated in healthy subjects and demonstrates prolonged bronchodilation in subjects with asthma and COPD.
Highly Cited
2009
Highly Cited
2009
Identifying conformational changes of the β2 adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators
The new β2 Adrenoceptor (β2AR) crystal structures provide a high-resolution snapshot of receptor interactions with two particular… 
Highly Cited
2009
Highly Cited
2009
Agonist Dose-dependent Phosphorylation by Protein Kinase A and G Protein-coupled Receptor Kinase Regulates β2 Adrenoceptor Coupling to Gi Proteins in Cardiomyocytes*
Adrenoceptors receptors (ARs) play a pivotal role in regulating cardiovascular response to catecholamines during stress. β2ARs… 
Highly Cited
2009
Highly Cited
2009
Inhibition of LTP by beta-amyloid is prevented by activation of β2 adrenoceptors and stimulation of the cAMP/PKA signalling pathway
Highly Cited
2005
Highly Cited
2005
Probing the β2 Adrenoceptor Binding Site with Catechol Reveals Differences in Binding and Activation by Agonists and Partial Agonists*
The β2 adrenergic receptor (β2AR) is a prototypical family A G protein-coupled receptor (GPCR) and an excellent model system for… 
Highly Cited
2005
Highly Cited
2005
Using synthetic lipids to stabilize purified beta2 adrenoceptor in detergent micelles.
2002
2002
β2 adrenoceptor promoter polymorphisms: extended haplotypes and functional effects in peripheral blood mononuclear cells
Background: The β2 adrenoceptor and its 5′ untranslated region contain a number of genetic variants. The aim of this study was to… 
Highly Cited
2000
Highly Cited
2000
Association analysis of β2 adrenoceptor polymorphisms with hypertension in a Black African population
Objective To determine whether or not β2 adrenoceptor polymorphism is a risk factor for the development of hypertension in a… 
Highly Cited
1998
Highly Cited
1998
Long- and short-acting beta2 adrenoceptor agonists: interactions in human contracted bronchi.
The aim of this study was to systematically compare the interaction of the long-acting beta2-adrenoceptor agonists formoterol and… 
Highly Cited
1997
Highly Cited
1997
Agonists induce conformational changes in transmembrane domains III and VI of the β2 adrenoceptor
Agonist binding to G protein‐coupled receptors is believed to promote a conformational change that leads to the formation of the… 
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