Mild to Moderate Muscular Symptoms with High-Dosage Statin Therapy in Hyperlipidemic Patients —The PRIMO Study
- E. Bruckert, G. Hayem, S. Dejager, C. Yau, B. Bégaud
- MedicineCardiovascular Drugs and Therapy
- 1 December 2005
It is demonstrated that mild to moderate muscular symptoms with high-dosage statin therapy may be more common and exert a greater impact on everyday lives than previously thought.
Trough imatinib plasma levels are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia.
- Stéphane Picard, K. Titier, F. Mahon
- Biology, MedicineBlood
- 15 April 2007
Monitoring of imatinib plasma levels could be very useful for the management of patients with CML or should at least be checked in the case of treatment failure or suboptimal response.
Use of oral corticosteroids in the United Kingdom.
- T. van Staa, H. Leufkens, L. Abenhaim, B. Bégaud, B. Zhang, C. Cooper
- MedicineQJM : monthly journal of the Association of…
- 1 February 2000
Investigation of the usage pattern of oral corticosteroids in a large sample representative of the general population in England and Wales found patients with arthropathies were most likely to use long-term, continuous treatment, and patients with chronic obstructive pulmonary disease least likely.
Admissions to hospital caused by adverse drug reactions: cross sectional incidence study
- P. Pouyanne, F. Haramburu, J. Imbs, B. Bégaud
- Medicine, Political ScienceBMJ : British Medical Journal
- 15 April 2000
The incidence of admissions caused by adverse drug reactions was calculated by conducting a prospective cross sectional study of a representative nationwide sample of medical wards in public hospitals in French teaching hospitals and general hospitals.
Improvement in gastrointestinal tolerability of the selective cyclooxygenase (COX)-2 inhibitor, meloxicam, compared with piroxicam: results of the Safety and Efficacy Large-scale Evaluation of…
- J. Dequeker, C. Hawkey, S. Papazoglou
- MedicineBritish Journal of Rheumatology
- 1 September 1998
The outcome of SELECT is consistent with that of the large-scale clinical trial of similar design and size which compared 7.5 mg meloxicam with 100 mg diclofenac in patients with osteoarthritis, and with a previous global analysis of the safety ofmeloxicam.
Patterns and correlates of benzodiazepine use in the French general population
- R. Lagnaoui, F. Depont, N. Moore
- Psychology, MedicineEuropean Journal of Clinical Pharmacology
- 28 August 2004
There remains a high proportion of long-term BZD users in the general French population, especially in the elderly, and the findings add the weight of opinion that messages concerning proper use of BZDs certainly need to be clarified and amplified.
Gastrointestinal tolerability of meloxicam compared to diclofenac in osteoarthritis patients. International MELISSA Study Group. Meloxicam Large-scale International Study Safety Assessment.
- C. Hawkey, A. Kahan, S. Papazoglou
- Medicine, PsychologyBritish Journal of Rheumatology
- 1 September 1998
The MELISSA trial confirms earlier studies suggesting that meloxicam has a significantly improved GI tolerability profile in comparison with other NSAIDs, including diclofenac, and provides support for the hypothesis that selective inhibition of COX-2 relative toCOX-1 might be an effective approach towards improved NSAID therapy.
Benzodiazepine use and risk of Alzheimer’s disease: case-control study
- Sophie Billioti de Gage, Y. Moride, B. Bégaud
- Medicine, PsychologyBMJ : British Medical Journal
- 9 September 2014
The stronger association observed for long term exposures reinforces the suspicion of a possible direct association, even if benzodiazepine use might also be an early marker of a condition associated with an increased risk of dementia.
[Imputation of the unexpected or toxic effects of drugs. Actualization of the method used in France].
- B. Bégaud, J. Evreux, J. Jouglard, G. Lagier
- MedicineThe´rapie (Paris)
- 1985
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