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beta-elemene

Known as: (1S,2S,4R)-2,4-diisopropenyl-1-methyl-1-vinylcyclohexane, (1alpha,2beta,4beta)-1-Methyl-2,4-bis(methylvinyl)-1- vinylcyclohexane 
One of the isomers of elemene, a lipid soluble sesquiterpene and the active component isolated from the Chinese medicinal herb Rhizoma zedoariae with… Expand
National Institutes of Health

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Sesquiterpenes

Papers overview

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Highly Cited
2010
Highly Cited
2010
Beta-elemene inhibits melanoma growth and metastasis via suppressing vascular endothelial growth factor-mediated angiogenesis
PurposeIt was to assess antiangiogenic effect of β-elemene in vitro and in vivo, and it was involved in inhibiting melanoma… Expand
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Highly Cited
2010
Highly Cited
2010
Antineoplastic effect of beta-elemene on prostate cancer cells and other types of solid tumour cells.
OBJECTIVES beta-Elemene, a natural compound extracted from over 50 different Chinese medicinal herbs and plants, has been… Expand
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Highly Cited
2008
Highly Cited
2008
Anti-tumor effect of beta-elemene in glioblastoma cells depends on p38 MAPK activation.
beta-Elemene, a natural plant drug extracted from Curcuma wenyujin, has been used as an antitumor drug for different tumors… Expand
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Highly Cited
2007
Highly Cited
2007
The rice (E)-beta-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes.
Terpenoids serve as both constitutive and inducible defense chemicals in many plant species, and volatile terpenes participate in… Expand
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Highly Cited
2007
Highly Cited
2007
In vitro combination characterization of the new anticancer plant drug beta-elemene with taxanes against human lung carcinoma.
Beta-elemene has recently raised interest in P.R. China as a novel antitumor plant drug isolated from the Chinese medicinal herb… Expand
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2007
2007
Interception of the Enzymatic Conversion of Farnesyl Diphosphate to 5‐Epi‐Aristolochene by Using a Fluoro Substrate Analogue: 1‐Fluorogermacrene A from (2E,6Z)‐6‐Fluorofarnesyl Diphosphate
Tobacco 5‐epi‐aristolochene synthase (TEAS) catalyzes the MgII‐dependent cyclizations and rearrangements of (E,E)‐farnesyl… Expand
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Highly Cited
2006
Highly Cited
2006
Essential oil analysis and anticancer activity of leaf essential oil of Croton flavens L. from Guadeloupe.
The leaf essential oil of Croton flavens L., a native plant from the Caribbean area used in traditional medicine, was extracted… Expand
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Highly Cited
2006
Highly Cited
2006
Assessing the quality of RCTs on the effect of beta-elemene, one ingredient of a Chinese herb, against malignant tumors.
OBJECTIVE To evaluate the quality of randomized controlled trials (RCTs) for Elemene injections, one ingredient of Chinese herb… Expand
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Highly Cited
2005
Highly Cited
2005
Antitumor effect of beta-elemene in non-small-cell lung cancer cells is mediated via induction of cell cycle arrest and apoptotic cell death.
  • G. Wang, X. Li, +7 authors Q. Li
  • Cellular and molecular life sciences : CMLS
  • 2005
    • Corpus ID: 22581721
Beta-elemene is a novel anticancer drug, which was extracted from the ginger plant. However, the mechanism of action of beta… Expand
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2005
2005
Characterization and Body Distribution of β-Elemene Solid Lipid Nanoparticles (SLN)
ABSTRACT Solid lipid nanoparticles (SLN) containing β-elemene, a volatile oil used for the treatment of cancer, were prepared by… Expand
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