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Antioxidant and cytotoxic flavonoids from the flowers of Melastoma malabathricum L.
Abstract Phytochemical and bioactivity studies of the flowers of Melastoma malabathricum L. (Melastomataceae) have been carried out. The ethyl acetate extract yielded three compounds, identified as
Characterization of the components present in the active fractions of health gingers (Curcuma xanthorrhiza and Zingiber zerumbet) by HPLC–DAD–ESIMS
Abstract Curcuma xanthorrhiza and Zingiber zerumbet are two of the most commonly used ingredients in Indo-Malaysian traditional medicines, health supplements and tonics. Recently, a number of
Combined xanthorrhizol-curcumin exhibits synergistic growth inhibitory activity via apoptosis induction in human breast cancer cells MDA-MB-231
These findings provide experimental support to the hypothesis that combined xanthorrhizol-curcumin showed synergistic growth inhibitory activity on MDA-MB-231 cells via apoptosis induction.
Inhibitory effect of compounds from Zingiberaceae species on human platelet aggregation.
Curcumin was the most effective antiplatelet compound as it inhibited AA-, collagen- and ADP-induced platelet aggregation with IC(50) values of 37.5, 60.9 and 45.7 microM, respectively.
Isolation and identification of radical scavenging and tyrosinase inhibition of polyphenols from Tibouchina semidecandra L.
Evaluation of the antioxidative activity on the crude extracts and pure compounds by electron spin resonance (ESR) and ultraviolet-visible (UV-vis) spectrophotometric assays showed that the pure isolated polyphenols and the EtOAc extract possessed strong antioxidative capabilities.
ABSTRACT Phytochemical and bioactivity studies of the leaves of Melastoma malabathricum L. (Melastomataceae) have been investigated. The n-hexane extract yielded -amyrin, patriscabatrine and
Chemical Composition of the Rhizome Oil of Alpinia conchigera Griff from Malaysia
ABSTRACT The essential oil isolated by hydrodistillation from the fresh rhizomes of Alpinia conchigera Griff was analyzed by capillary GC and GC/MS. More than 40 constituents were present in the oil,
Anti-inflammatory activities of cucurbitacin E isolated from Citrullus lanatus var. citroides: role of reactive nitrogen species and cyclooxygenase enzyme inhibition.
The results showed that LPS/INF-γ increased NO production in RAW264.7 macrophages, whereas L-NAME and CE curtailed it, and it could be concluded that CE is potentially useful in treating inflammation through the inhibition of COX and RNS but not ROS.
Pharmacological Mechanisms Underlying Gastroprotective Activities of the Fractions Obtained from Polygonum minus in Sprague Dawley Rats
The ethyl acetate:methanol 1:1 v/v fraction was considered to be the best fraction for mucous protection in the ethanol induction model and the mechanisms underlying this protection were attributed to the synthesis of antioxidants and PGE2.