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benzene oxide

Known as: 7-oxabicyclo(4.1.0)hepta-2,4-diene 
National Institutes of Health

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1 relation

Broader (1)

Cyclohexanes

Papers overview

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2012
2012
Reactions of benzene oxide, a reactive metabolite of benzene, with model nucleophiles and DNA
Reactivity of benzene oxide (BO), a reactive metabolite of benzene, was studied in model reactions with biologically relevant S… 
2008
2008
Evidence from mechanistic probes for distinct hydroperoxide rearrangement mechanisms in the intradiol and extradiol catechol dioxygenases.
Three mechanistic probes were used to investigate whether the Criegee rearrangement step of catechol 1,2-dioxygenase (CatA) from… 
2006
2006
Progress of Epidemiological and Molecular Epidemiological Studies on Benzene in China
Abstract:  Benzene is an organic solvent that has been used in industry for about 100 years throughout the world. Since 1973, a… 
Review
2005
Review
2005
Use of genetically modified mouse models to assess pathways of benzene-induced bone marrow cytotoxicity and genotoxicity.
2001
2001
Chemoprevention of benzene-induced bone marrow and pulmonary genotoxicity.
Our earlier studies documented the ability of 7,8-diacetoxy-4-methylcoumarin (DAMC) to cause irreversible inhibition of… 
Highly Cited
1998
Highly Cited
1998
Formation of hemoglobin and albumin adducts of benzene oxide in mouse, rat, and human blood.
Little is known about the formation and disposition of benzene oxide (BO), the initial metabolite arising from oxidation of… 
1993
1993
Biomarkers of human exposure to benzene.
Three biomarkers for benzene exposure were developed. The first biomarker, muconic acid in urine, results from the ring opening… 
1992
1992
Isolation and characterization of two benzene-derived hemoglobin adducts in vivo in rats.
The present study was aimed at the characterization of the major adducts formed by reaction of the metabolites of [14C]benzene… 
1990
1990
Lung tumorigenicity of benzene oxide, benzene dihydrodiols and benzene diolepoxides in the BLU:Ha newborn mouse assay.
Metabolic activation of benzene may occur by a pathway analogous to that accepted for polynuclear aromatic hydrocarbons (PAHs… 
1986
1986
Comparison of the metabolism of benzene and its metabolite phenol in rat liver microsomes.
It has been known for many years that chronic exposure to benzene leads to bone marrow depression and aplastic anemia and in… 
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