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Hematotoxicity in Workers Exposed to Low Levels of Benzene
Benzene is known to have toxic effects on the blood and bone marrow, but its impact at levels below the U.S. occupational standard of 1 part per million (ppm) remains uncertain. In a study of 250Expand
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A comprehensive evaluation of within- and between-worker components of occupational exposure to chemical agents.
A database of approximately 20,000 chemical exposures has been constructed in close co-operation between the School of Public Health of the University of North Carolina at Chapel Hill and theExpand
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Assessment of long-term exposures to toxic substances in air.
  • S. Rappaport
  • Environmental Science, Medicine
  • The Annals of occupational hygiene
  • 1 February 1991
Because airborne exposure varies greatly over time and between individual workers, occupational hygienists should adopt sampling strategies which recognize the inherent statistical nature ofExpand
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Occupational Exposure to Formaldehyde, Hematotoxicity, and Leukemia-Specific Chromosome Changes in Cultured Myeloid Progenitor Cells
There are concerns about the health effects of formaldehyde exposure, including carcinogenicity, in light of elevated indoor air levels in new homes and occupational exposures experienced by workersExpand
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Using urinary biomarkers to elucidate dose-related patterns of human benzene metabolism.
Although the toxicity of benzene has been linked to its metabolism, the dose-related production of metabolites is not well understood in humans, particularly at low levels of exposure. WeExpand
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Health and environmental consequences of the world trade center disaster.
The attack on the World Trade Center (WTC) created an acute environmental disaster of enormous magnitude. This study characterizes the environmental exposures resulting from destruction of the WTCExpand
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Implications of the exposome for exposure science
  • S. Rappaport
  • Biology, Medicine
  • Journal of Exposure Science and Environmental…
  • 2011
During the 1920s, the forerunners of exposure science collaborated with health professionals to investigate the causes of occupational diseases. With the birth of U.S. regulatory agencies in theExpand
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Environment and Disease Risks
A new paradigm is needed to assess how a lifetime of exposure to environmental factors affects the risk of developing chronic diseases. Although the risks of developing chronic diseases areExpand
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Excessive exposure to silica in the US construction industry.
Exposures to respirable dust and silica were investigated among 36 construction sites in the USA. Personal measurements (n = 151) were analyzed from 80 workers in four trades, namely bricklayers,Expand
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Modeling Human Metabolism of Benzene Following Occupational and Environmental Exposures
We used natural spline (NS) models to investigate nonlinear relationships between levels of benzene metabolites (E,E-muconic acid, S-phenylmercapturic acid, phenol, hydroquinone, and catechol) andExpand
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