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- Publications
- Influence
Hematotoxicity in Workers Exposed to Low Levels of Benzene
Benzene is known to have toxic effects on the blood and bone marrow, but its impact at levels below the U.S. occupational standard of 1 part per million (ppm) remains uncertain. In a study of 250… Expand
A comprehensive evaluation of within- and between-worker components of occupational exposure to chemical agents.
- H. Kromhout, E. Symanski, S. Rappaport
- Environmental Science, Medicine
- The Annals of occupational hygiene
- 1 June 1993
A database of approximately 20,000 chemical exposures has been constructed in close co-operation between the School of Public Health of the University of North Carolina at Chapel Hill and the… Expand
Assessment of long-term exposures to toxic substances in air.
- S. Rappaport
- Environmental Science, Medicine
- The Annals of occupational hygiene
- 1 February 1991
Because airborne exposure varies greatly over time and between individual workers, occupational hygienists should adopt sampling strategies which recognize the inherent statistical nature of… Expand
Occupational Exposure to Formaldehyde, Hematotoxicity, and Leukemia-Specific Chromosome Changes in Cultured Myeloid Progenitor Cells
- L. Zhang, Xiaojiang Tang, +31 authors Q. Lan
- Biology, Medicine
- Cancer Epidemiology, Biomarkers & Prevention
- 1 January 2010
There are concerns about the health effects of formaldehyde exposure, including carcinogenicity, in light of elevated indoor air levels in new homes and occupational exposures experienced by workers… Expand
Using urinary biomarkers to elucidate dose-related patterns of human benzene metabolism.
- S. Kim, R. Vermeulen, +9 authors S. Rappaport
- Chemistry, Medicine
- Carcinogenesis
- 1 April 2006
Although the toxicity of benzene has been linked to its metabolism, the dose-related production of metabolites is not well understood in humans, particularly at low levels of exposure. We… Expand
Health and environmental consequences of the world trade center disaster.
- P. Landrigan, P. Lioy, +10 authors C. Small
- Medicine
- Environmental health perspectives
- 1 May 2004
The attack on the World Trade Center (WTC) created an acute environmental disaster of enormous magnitude. This study characterizes the environmental exposures resulting from destruction of the WTC… Expand
Implications of the exposome for exposure science
- S. Rappaport
- Biology, Medicine
- Journal of Exposure Science and Environmental…
- 2011
During the 1920s, the forerunners of exposure science collaborated with health professionals to investigate the causes of occupational diseases. With the birth of U.S. regulatory agencies in the… Expand
Environment and Disease Risks
- S. Rappaport, M. Smith
- Biology, Medicine
- Science
- 22 October 2010
A new paradigm is needed to assess how a lifetime of exposure to environmental factors affects the risk of developing chronic diseases. Although the risks of developing chronic diseases are… Expand
Excessive exposure to silica in the US construction industry.
- S. Rappaport, M. Goldberg, P. Susi, R. Herrick
- Environmental Science, Medicine
- The Annals of occupational hygiene
- 1 March 2003
Exposures to respirable dust and silica were investigated among 36 construction sites in the USA. Personal measurements (n = 151) were analyzed from 80 workers in four trades, namely bricklayers,… Expand
Modeling Human Metabolism of Benzene Following Occupational and Environmental Exposures
- S. Kim, R. Vermeulen, +9 authors S. Rappaport
- Chemistry, Medicine
- Cancer Epidemiology Biomarkers & Prevention
- 1 November 2006
We used natural spline (NS) models to investigate nonlinear relationships between levels of benzene metabolites (E,E-muconic acid, S-phenylmercapturic acid, phenol, hydroquinone, and catechol) and… Expand