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benralizumab

Known as: BIW-8405, MEDI-563, Anti-CD125 Humanized Monoclonal Antibody, IgG1-kappa 
An afucosylated, humanized monoclonal antibody against the alpha chain of the interleukin-5 receptor (IL-5Ra), with potential anti-asthmatic activity… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Antibodies, Monoclonal, Humanized
antigen binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Postbronchodilator lung function improvements with benralizumab for patients with severe asthma
proteins: an NMR study on Blomia tropicalis major allergen. Structure. 2008;16(1):125-136. 3. Chan SL, Ong TC, Gao YF, et al… 
Review
2020
Review
2020
Effect of monoclonal antibody drug therapy on mucosal biomarkers in airway disease: A systematic review
Monoclonal antibody therapies have a growing role in treating refractory airway disease. 
2019
2019
Rapid Effect of Benralizumab for Hypereosinophilia in a Case of Severe Asthma with Eosinophilic Chronic Rhinosinusitis
A 56-year-old man with severe asthma underwent bronchial thermoplasty (BT). However, his asthma exacerbated and hypereosinophilia… 
2019
2019
Eosinophils depletion therapy for severe asthma management following favorable response to mepolizumab
2019
2019
Biologics and Bronchial Thermoplasty for severe refractory asthma treatment: From eligibility criteria to real practice. A cross-sectional study.
2018
2018
Emerging biological therapies for treating chronic obstructive pulmonary disease: A pairwise and network meta-analysis.
2018
2018
Development of a robust reporter gene based assay for the bioactivity determination of IL‐5‐targeted therapeutic antibodies
2018
2018
Selection of a Ligand-Binding Neutralizing Antibody Assay for Benralizumab: Comparison with an Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) Cell-Based Assay
Assessment of anti-drug antibodies (ADAs) for neutralizing activity is important for the clinical development of… 
Review
2015
Review
2015
Emerging therapeutic options for the treatment of patients with symptomatic asthma.
Review
2011
Review
2011
Current update on eosinophilic lung diseases and anti-IL-5 treatment.
Peripheral blood eosinophilia and eosinophilic lung inflammation are common in a variety of pulmonary conditions, including… 
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