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belotecan

Known as: 7-(2-(N-isopropylamino)ethyl)camptothecin 
The active ingredient in a substance being studied in the treatment of small cell lung cancer and other types of cancer. It blocks certain enzymes… 
National Institutes of Health

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Related topics

5 relations

Narrower (1)

CKD 602

Broader (2)

CamptothecinTopoisomerase I Inhibitors
analogs & derivativesbelotecan hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Lesser Toxicities of Belotecan in Patients with Small Cell Lung Cancer: A Retrospective Single-Center Study of Camptothecin Analogs
Purpose. Topotecan and belotecan are camptothecin derivatives that are used to treat small cell lung cancer (SCLC). This study… 
2013
2013
A multicenter phase II study of belotecan, a new camptothecin analogue, in elderly patients with previously untreated, extensive-stage small cell lung cancer
PurposeBelotecan is a new camptothecin analogue and a potent topoisomerase I inhibitor. The aim of this phase II study was to… 
2012
2012
In vitro chemosensitivity using the histoculture drug response assay in human epithelial ovarian cancer.
The choice of chemotherapeutic drugs to treat patients with epithelial ovarian cancer has not depended on individual patient… 
2012
2012
Antitumor activity of CKD-602, a camptothecin derivative, in a mouse glioma model
2010
2010
The Efficacy and Toxicity of Belotecan (CKD-602), A Camptothecin Analogue Topoisomerase I Inhibitor, in Patients with Recurrent or Refractory Epithelial Ovarian Cancer
Abstract This study evaluated the efficacy and toxicity of belotecan (CKD-602), a new camptothecin analogue topoisomerase i… 
2010
2010
The efficacy and toxicity of belotecan (CKD-602), a camptothericin analogue topoisomerase I inhibitor, in patients with recurrent or refractory epithelial ovarian cancer.
This study evaluated the efficacy and toxicity of belotecan (CKD-602), a new camptothecin analogue topoisomerase i inhibitor, in… 
2009
2009
Multicenter phase 2 study of belotecan, a new camptothecin analog, and cisplatin for chemotherapy‐naive patients with extensive‐disease small cell lung cancer
The objective of this study was to investigate the efficacy of belotecan, a new camptothecin analog, combined with cisplatin for… 
2009
2009
Efficacy and Toxicity of Belotecan With and Without Cisplatin in Patients With Recurrent Ovarian Cancer
Objective:This study was performed to determine the safety and efficacy of belotecan, a new camptothecin analogue and potent… 
2009
2009
CKD-602, a camptothecin derivative, inhibits proliferation and induces apoptosis in glioma cell lines.
CKD-602 7-[2-(N-isopropylamino)ethyl]-(20S)-camptothecin, belotecan) is a synthetic water-soluble camptothecin derivative and… 
2007
2007
Effect of probenecid on the biliary excretion of belotecan
The purpose of this study was to investigate the effect of probenecid, an inhibitor of the MRP2/ ABCC transporter, on the… 
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