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azelastine

Known as: 4-(P-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone, Azelastina, azelastine [Chemical/Ingredient] 
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (7)

A 5610AllergodilAstelinAstepro
Allergic ConjunctivitisAzelastine hydrochlorideAzelastine hydrochloride 0.206 MG/ACTUAT Metered Dose Nasal Spray [Astepro]Drug Allergy

Broader (5)

Anti-Allergic AgentsBronchodilator AgentsHistamine H1 Antagonists, Non-SedatingLipoxygenase Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Azelastine nasal spray and desloratadine tablets in pollen-induced seasonal allergic rhinitis: a pharmacodynamic study of onset of action and efficacy
ABSTRACT Objective: To assess the efficacy and onset of action of azelastine nasal spray and desloratadine tablets in patients… 
Highly Cited
2001
Highly Cited
2001
Inhibitory effects of CYP3A4 substrates and their metabolites on P-glycoprotein-mediated transport.
1996
1996
Quantification of conjunctival vascular reaction by digital imaging.
Highly Cited
1994
Highly Cited
1994
Effectiveness of Azelastine Nasal Solution in Seasonal Allergic Rhinitis
Azelastine is a novel antiallergy medication currently under investigation for the treatment of allergic rhinitis and asthma… 
1994
1994
Inhibition of cytokine production from human peripheral blood leukocytes by anti-allergic agents in vitro.
1993
1993
Effect of azelastine on substance P content in bronchoalveolar and nasal lavage fluids of patients with allergic asthma
The study was carried out to investigate the effect of azelastine on the Substance P (SP) concentration in bronchoalveolar (BAL… 
1989
1989
Inhibition of allergic and nonallergic leukotriene C4 formation and histamine secretion by azelastine: implication for its mechanism of action.
Azelastine, an orally effective antiasthmatic agent, has been reported to inhibit antihistamine-resistant, leukotriene-mediated… 
Highly Cited
1987
Highly Cited
1987
Effect of azelastine on the release and action of leukotriene C4 and D4.
The effect of azelastine on the release of leukotriene C4 and D4 (LTC4 and LTD4), and the antagonistic action of the drug against… 
Highly Cited
1985
Highly Cited
1985
Inhibition of allergic histamine release by azelastine and selected antiallergic drugs from rabbit leukocytes.
The ability of azelastine to inhibit allergic histamine release from rabbit mixed leukocytes was studied and compared with… 
1984
1984
Inhibitory effects of various drugs on phorbol myristate acetate and n-formyl methionyl leucyl phenylalanine induced O2- production in polymorphonuclear leukocytes.
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