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azelastine

Known as: 4-(P-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone, Azelastina, azelastine [Chemical/Ingredient] 
 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
BACKGROUND Moderate-to-severe allergic rhinitis (AR) is a challenge to treat, with many patients using multiple therapies and… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT Objective: To assess the efficacy and onset of action of azelastine nasal spray and desloratadine tablets in patients… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Azelastine nasal spray and oral cetirizine are selective histamine H(1)-receptor antagonists that are approved in the… Expand
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Highly Cited
1998
Highly Cited
1998
  • Shichijo, Inagaki, +6 authors Nagai
  • Clinical and experimental allergy : journal of…
  • 1998
  • Corpus ID: 9463801
A method for generating human mast cells in vitro was recently established. Little is known about the pharmacological profiles of… Expand
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Highly Cited
1997
Highly Cited
1997
The mast cell plays a pivotal role in initiating allergic inflammation by secreting several cytokines including TNF-alpha, in… Expand
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Highly Cited
1997
Highly Cited
1997
Background Azelastine is a selective H1‐receptor antagonist, which has previously been demonstrated to be effective in the… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND It is well known that allergen-specific nasal challenge (ASNC) is a fruitful tool with which to evaluate antiallergic… Expand
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Highly Cited
1989
Highly Cited
1989
Azelastine is a new investigational drug used to treat rhinitis and asthma. In addition to described actions that include… Expand
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Highly Cited
1987
Highly Cited
1987
Azelastine is an orally effective inhibitor of mediator activity in allergic reactions and has also been demonstrated to have… Expand
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Highly Cited
1983
Highly Cited
1983
Azelastine is a novel, orally effective, long-acting, antiallergic agent. The ability of azelastine to influence calcium… Expand
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