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Azelastine hydrochloride
Known as:
1(2H)-Phthalazinone, 4-((4-Chlorophenyl)methyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, Monohydrochloride
, 4-((4-chlorophenyl)methyl)-2- (hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)- phthalazinone HCl
, azelastine hcl
Â
The hydrochloride salt form of azelastine, a phthalazinone derivative with antihistaminergic activity. Azelastine hydrochloride competes with…Â
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National Institutes of Health
Topic mentions per year
Topic mentions per year
1981-2018
0
5
10
15
1981
2018
Related topics
Related topics
16 relations
Narrower (4)
A 5610
Astelin
Astepro
Dymista
Allergic Conjunctivitis
Drug Allergy
Rhinitis, Allergic, Perennial
Rhinitis, Vasomotor
(More)
Broader (7)
Anti-Allergic Agents
Anti-Inflammatory Agents, Non-Steroidal
Bronchodilator Agents
Histamine H1 Antagonists
(More)
Related mentions per year
Related mentions per year
1936-2019
1940
1960
1980
2000
2020
Azelastine hydrochloride
Drug Allergy
Anti-Inflammatory Agents, Non-Steroidal
Bronchodilator Agents
Histamine H1 Antagonists
Anti-Allergic Agents
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Double-blind, placebo-controlled study of azelastine and fluticasone in a single nasal spray delivery device.
Frank C. Hampel
,
Paul H Ratner
,
+4 authors
Harry J. Sacks
Annals of allergy, asthma & immunology : official…
2010
BACKGROUND A proof-of-concept study suggested that combination therapy with commercial azelastine hydrochloride nasal spray and…Â
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Is this relevant?
2008
2008
Combination therapy with azelastine hydrochloride nasal spray and fluticasone propionate nasal spray in the treatment of patients with seasonal allergic rhinitis.
Paul H Ratner
,
Frank Hampel
,
+4 authors
Harry J. Sacks
Annals of allergy, asthma & immunology : official…
2008
BACKGROUND To our knowledge, there are no published studies that evaluated the efficacy of azelastine hydrochloride nasal spray…Â
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Is this relevant?
2002
2002
A study of intranasal distribution of azelastine hydrochloride aqueous nasal spray with different spray techniques.
Nicoleta Bateman
,
Andrew D Whymark
,
Nicholas Clifton
,
Tim J Woolford
Clinical otolaryngology and allied sciences
2002
Topical aqueous nasal sprays are widely used in treating patients with a variety of nasal diseases. Previous studies have…Â
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2001
2001
Efficacy of azelastine nasal spray in the treatment of vasomotor (perennial nonallergic) rhinitis.
Charles H Banov
,
Pamela Lieberman
Annals of allergy, asthma & immunology : official…
2001
BACKGROUND Azelastine hydrochloride is an antihistamine with anti-inflammatory properties that is available in the United States…Â
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Is this relevant?
2001
2001
Evaluation of the efficacy of olopatadine hydrochloride 0.1% ophthalmic solution and azelastine hydrochloride 0.05% ophthalmic solution in the conjunctival allergen challenge model.
Diane L. Spangler
,
George W. Bensch
,
Gregg J Berdy
Clinical therapeutics
2001
BACKGROUND Olopatadine hydrochloride 0.1% ophthalmic solution and azelastine hydrochlofide 0.05% ophthalmic solution are 2…Â
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Is this relevant?
1999
1999
Inhibitory effects of azelastine hydrochloride in alcohol-induced asthma.
Atsuyoshi Takao
,
Teruhumi Shimoda
,
+4 authors
Sigeru Kohno
Annals of allergy, asthma & immunology : official…
1999
BACKGROUND Alcohol-induced bronchoconstriction is due to high blood concentrations of acetaldehyde, a metabolic product of…Â
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1998
1998
Antitussive effect of azelastine hydrochloride in patients with bronchial asthma.
Takanobu Shioya
,
N. Ito
,
+6 authors
Masahiko Miura
Arzneimittel-Forschung
1998
To investigate the efficacy of azelastine hydrochloride (azelastine, CAS 79307-93-0, Azeptin) in suppressing cough, 22 bronchial…Â
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1997
1997
Urinary N-methylhistamine in asthmatic children receiving azelastine hydrochloride.
S. Takei
,
Atsushi Shimago
,
Misato Iwashita
,
Takuya Kumamoto
,
K. Kamuro
,
K. Miyata
Annals of allergy, asthma & immunology : official…
1997
BACKGROUND Histamine has a particular role in the pathogenesis of bronchial asthma, and many antiallergic drugs have been…Â
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1997
1997
Suppression by azelastine hydrochloride of NF-kappa B activation involved in generation of cytokines and nitric oxide.
K. Yoneda
,
T. Yamamoto
,
Eisaku Ueta
,
T. Osaki
Japanese journal of pharmacology
1997
The influence of the anti-allergy agent azelastine hydrochloride (Azeptin) on NF-kappa B activation associated with the…Â
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1995
1995
Tolerability and pharmacokinetics of single and multiple doses of azelastine hydrochloride in elderly volunteers.
Gary F. Peter
,
Peter Romeis
,
Harald O. Borbe
,
K M Büker
,
H. Riethmüller-Winzen
Arzneimittel-Forschung
1995
The tolerability and pharmacokinetics of azelastine hydrochloride (CAS 73907-93-0, A-05610) after single and multiple dosing (4.4…Â
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