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azaspiracid

Known as: Azaspiracid-1 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Marine ToxinsSpiro Compounds

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons.
Azaspiracids (AZAs) are a group of marine toxins recently described that currently includes 20 members. Not much is known about… 
2010
2010
Cytotoxic effect of palytoxin on mussel.
Highly Cited
2007
Highly Cited
2007
Effects of azaspiracid-1, a potent cytotoxic agent, on primary neuronal cultures. A structure-activity relationship study.
Azaspiracids (AZAs) are marine phycotoxins with an unknown mechanism of action, implicated in human intoxications. We… 
2007
2007
Total synthesis of (+)-azaspiracid-1. Part II: synthesis of the EFGHI sulfone and completion of the synthesis.
With a practical synthesis of the ABCD aldehyde in hand (2, Scheme 1), herein we describe our progress that culminated in the… 
2007
2007
Total synthesis of (+)-azaspiracid-1. Part I: Synthesis of the fully elaborated ABCD aldehyde.
wede-scribeourefforts,whichculminatedinasynthesisof(+)-azaspiracid-1 (ent-2, Scheme1). This target requires… 
Highly Cited
2006
Highly Cited
2006
Total synthesis and structural elucidation of azaspiracid-1. Final assignment and total synthesis of the correct structure of azaspiracid-1.
The molecular structure of azaspiracid-1, a neurotoxin isolated from mussels, has been elucidated by total synthesis which also… 
Highly Cited
2006
Highly Cited
2006
Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure.
Syntheses of the three key building blocks (65, 98, and 100) required for the total synthesis of the proposed structure of… 
2006
2006
Total synthesis and structural elucidation of azaspiracid-1. Synthesis-based analysis of originally proposed structures and indication of their non-identity to the natural product.
The key building blocks (6, 7, and 8) for the intended construction of the originally proposed structures of azaspiracid-1, a… 
Highly Cited
2001
Highly Cited
2001
Structures of Azaspiracid Analogs, Azaspiracid-4 and Azaspiracid-5, Causative Toxins of Azaspiracid Poisoning in Europe
Two new analogs of azaspiracid, azaspiracid-4 and azaspiracid-5, isolated from the mussel Mytilus edulis, involved in a newly… 
2001
2001
Synthesis of the ABCD Ring System of Azaspiracid.
Previously attempted spirocyclizations to form the ABCD ring system of azaspiracid (1) have proven unsuccessful owing to the… 
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