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arteflene

National Institutes of Health

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4 relations

Broader (4)

AntimalarialsArtemisininsBridged Bicyclo Compounds, HeterocyclicStyrenes

Papers overview

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2006
2006
Diels-Alder/thiol-olefin co-oxygenation approach to antimalarials incorporating the 2,3-dioxabicyclo[3.3.1]nonane pharmacophore.
2004
2004
Hepatocellular bioactivation and cytotoxicity of the synthetic endoperoxide antimalarial arteflene.
1999
1999
Characterization of the Main Radical and Products Resulting from a Reductive Activation of the Antimalarial Arteflene (Ro 42-1611).
The peroxide-containing antimalarial drug arteflene (Ro 42-1611) generates an alkyl radical after the reductive homolytic… 
1995
1995
Antigonococcal activity of 11 drugs used for therapy or prophylaxis of malaria.
1994
1994
Efficacy of Ro 42-1611 (arteflene) in the treatment of patients with mild malaria: a clinical trial in Cameroon.
The novel antimalarial Ro 42-1611 (arteflene) was evaluated for safety and efficacy in an open, non-comparative study of patients… 
1994
1994
Total malaria eradication - are we any closer?
The goal of eradicating malaria, set in the 1950s, has still not been achieved today. But are we any closer? Estimates of the… 
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