aptamer

Known as: aptamers 
Double-stranded DNA or single-stranded RNA oligonucleotide sequences with the capacity to recognize target molecules with high affinity and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Nucleic acid aptamers can be selected from pools of random-sequence oligonucleotides to bind a wide range of biomedically… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND The interrogation of proteomes ("proteomics") in a highly multiplexed and efficient manner remains a coveted and… (More)
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Highly Cited
2009
Highly Cited
2009
Prostate cancer cells expressing prostate-specific membrane antigen (PSMA) have been targeted with RNA aptamer–small interfering… (More)
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Highly Cited
2008
Highly Cited
2008
Cisplatin is used to treat a variety of tumors, but dose limiting toxicities or intrinsic and acquired resistance limit its… (More)
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Highly Cited
2007
Highly Cited
2007
We report a novel quantum dot (QD)-aptamer(Apt)-doxorubicin (Dox) conjugate [QD-Apt(Dox)] as a targeted cancer imaging, therapy… (More)
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Review
2006
Review
2006
Aptamers are oligonucleotide ligands that are selected for high-affinity binding to molecular targets. Pegaptanib sodium (Macugen… (More)
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Highly Cited
2006
Highly Cited
2006
Targeted uptake of therapeutic nanoparticles in a cell-, tissue-, or disease-specific manner represents a potentially powerful… (More)
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Highly Cited
2006
Highly Cited
2006
Nucleic acids that bind to cells and are subsequently internalized could prove to be novel delivery reagents. An anti-prostate… (More)
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Highly Cited
2004
Highly Cited
2004
Nucleic acid ligands (aptamers) are potentially well suited for the therapeutic targeting of drug encapsulated controlled release… (More)
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Review
2000
Review
2000
Nucleic acid molecules play crucial roles in diverse biological processes including the storage, transport, processing, and… (More)
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