High-throughput protein arrays: prospects for molecular diagnostics.

@article{Walter2002HighthroughputPA,
  title={High-throughput protein arrays: prospects for molecular diagnostics.},
  author={Gerald Walter and Konrad B{\"u}ssow and Angelika Lueking and J{\"o}rn Gl{\"o}kler},
  journal={Trends in molecular medicine},
  year={2002},
  volume={8 6},
  pages={250-3}
}
High-throughput protein arrays allow the miniaturized and parallel analysis of large numbers of diagnostic markers in complex samples. Using automated colony picking and gridding, cDNA or antibody libraries can be expressed and screened as clone arrays. Protein microarrays are constructed from recombinantly expressed, purified, and yet functional proteins, entailing a range of optimized expression systems. Antibody microarrays are becoming a robust format for expression profiling of whole… CONTINUE READING