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aprikalim

Known as: N-methyl-2-(3-pyridyl)tetrahydrothiopyran-2-carbothioamide-1-oxide 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (4)

Antihypertensive AgentsPicolinesPyransVasodilator Agents

Narrower (2)

RP 49356RP 52891

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1999
Review
1999
Cellular and molecular therapeutic targets for treatment of contractile dysfunction after cardioplegic arrest.
1997
1997
Superiority of hyperpolarizing to depolarizing cardioplegia in protection of coronary endothelial function.
Highly Cited
1996
Highly Cited
1996
Potassium channel openers prevent potassium-induced calcium loading of cardiac cells: possible implications in cardioplegia.
1996
1996
Myocardial protection with potassium-channel openers is as effective as St. Thomas' solution in the rabbit heart.
Highly Cited
1995
Highly Cited
1995
Stretch-activated channel blockers modulate cell volume in cardiac ventricular myocytes.
1994
1994
Altered Control of Vascular Tone by Adenosine Triphosphate- Sensitive Potassium Channels in Rats With Cirrhosis
Highly Cited
1993
Highly Cited
1993
Elective cardiac arrest with a hyperpolarizing adenosine triphosphate-sensitive potassium channel opener. A novel form of myocardial protection?
1993
1993
Inhibition of contractions of the isolated human myometrium by potassium channel openers.
1993
1993
Effects of P1060 and aprikalim on whole‐cell currents in rat portal vein; inhibition by glibenclamide and phentolamine
1 Smooth muscle cells of the rat portal vein were dispersed by enzymatic treatment and recordings of whole‐cell currents were… 
Highly Cited
1991
Highly Cited
1991
The new K+ channel opener Aprikalim (RP 52891) reduces experimental infarct size in dogs in the absence of hemodynamic changes.
The objective of the present study was to determine the effect of a novel K+ channel opener, Aprikalim (RP 52891; [trans-(-)-N… 
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