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Vinpocetine (VPN) is a synthetic ethyl-ester derivative of the alkaloid apovincamine from Vinca minor leaves. VPN is a selective… Expand Eight new indole alkaloids, alpneumines A-H (1-8) were isolated from the Malaysian Alstonia pneumatophora (Apocynaceae) and their… Expand INTRODUCTION
Hemorheological factors play an important role in the pathomechanism of ischemic cerebrovascular disorders. Abnormal… Expand Synthesis of oxidative metabolites of ethyl cisand hydroxyethyl trans-apovincaminates have been described. For cis-metabolite 8… Expand SummaryBy separating the total alkaloids ofV.erecta according to their basicities in an APS, in addition to bases known… Expand BACKGROUND
Vinpocetine is a synthetic ethyl ester of apovincamine, a vinca alkaloid obtained from the leaves of the Lesser… Expand The aim of the study was to assess the safety and feasibility of a clinical trial on the effect of vinpocetine, a synthetic ethyl… Expand Changes in the pericapillary microenvironment of adult (18-month-old) and senescent (27 1/2-month-old) Fischer-344 rats treated… Expand In a double‐blind clinical trial, vinpocetine, a synthetic ethyl ester of apovincamine, was shown to effect significant… Expand A new phthalidyl derivative of apovincamine, (3 alpha,16 alpha)-eburnamenine-14 carboxylic acid phthalidyl ester (AF 698), has… Expand