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Tropical filamentous marine cyanobacteria have emerged as a viable source of novel bioactive natural products for drug discovery… Expand Two polyketide metabolites, nhatrangins A (1) and B (2), were isolated from a Vietnamese collection of Lyngbya majuscula. These… Expand 1. Intoduction 4348 2. Oxolane Macrodiolides 4348 2.1. Pamamycin 607 (1) 4348 2.1.1. Thomas Total Synthesis20 4349 2.1.2. Lee… Expand Okadaic acid is a polyether compound of a C38 fatty acid, isolated from a black sponge, Halichondria okadai. Previous studies… Expand Publisher Summary This chapter presents two classes of 12- O -tetradecanoylphorbol-13-aceta (TPA)-type tumor promoters… Expand In the two-stage model of skin carcinogenesis, it is believed that initiators bind to DNA and that tumor promoters such as… Expand : We have found that maximum stimulation (greater than 10-fold) of kinase activity of a bovine brain preparation of calcium- and… Expand We have compared the activities of aplysiatoxin and debromoaplysiatoxin, two polyacetate marine algae toxins, with teleocidin, a… Expand Aplysiatoxin is a new class of potent tumor promoter and debromoaplysiatoxin may be a weak promoter. Aplysiatoxin and… Expand