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aplysiatoxin

National Institutes of Health

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Lyngbya Toxins

Papers overview

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2017
2017
US 005643948 A 11 Patent Number : 45 ) Date of Patent : 5 , 643 , 948 Jul
63) Continuation-in-part of Ser. No. 980,907, Nov.24, 1992, and Ser. No. 664,397, Mar. 4, 1991, which is a continuation-in part… 
1996
1996
Suppression of IL-1.ALPHA. production by PKC activators in human umbilical vein endothelial cells.
In human umbilical vein endothelial cells, treatment with tumor necrosis factor (TNF) -α stimulated the production of… 
1987
1987
Effects of various tumor promoters on expression of cartilage phenotypes in rabbit costal chondrocytes in culture.
12-O-Tetradecanoylphorbol-13-acetate (TPA), a skin tumor-promoting phorbol ester, and teleocidin and aplysiatoxin, which are… 
1987
1987
Colony formation enhancement of rat tracheal and nasal epithelial cells by polyacetate, indole alkaloid, and phorbol ester tumor promoters.
The phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA), teleocidin and two polyacetate tumor promoters (aplysiatoxin and… 
1986
1986
Binding studies of [3H]lyngbyatoxin A and [3H]debromoaplysiatoxin to the phorbol ester receptor in a mouse epidermal particulate fraction.
The preparation of [3H]lyngbyatoxin A by catalytic triton-proton exchange of lyngbyatoxin A and [3H]debromoaplysiatoxin by… 
Highly Cited
1985
Highly Cited
1985
Activation of protein kinase C by tumor promoting phorbol esters, teleocidin and aplysiatoxin in the absence of added calcium
: We have found that maximum stimulation (greater than 10-fold) of kinase activity of a bovine brain preparation of calcium- and… 
1985
1985
Induced secretion of a Mr 46,000 protein by cultured human hepatoma cells treated with tumor promoters.
Human hepatoma cells, HuH-6 Cl-5, were treated with 12-O-tetradecanoylphorbol-13-acetate at concentrations of 1 ng/ml to 10… 
1984
1984
Activation of cytotoxic activity of human blood lymphocytes by tumor-promoting compounds.
Three categories of tumor promoters and chemically related but inactive substances were tested for their effect on the cytotoxic… 
1983
1983
Increase in the synthesis of a Mr 32,000 protein in BALB/c 3T3 cells treated with tumor-promoting indole alkaloids or polyacetates.
The synthesis of a unique protein with a molecular weight of 32,000 (p32) in BALB/c 3T3 cells has been shown previously to… 
1983
1983
Molecular mechanisms of tumor promotion and multistage carcinogenesis.
: Carcinogenesis is a multistep process resulting from a complex interaction between multiple factors, both environmental and… 
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