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apicidin

Known as: cyclo(N-O-methyl-tryptophyl-isoleucyl-pipecolinyl-2-amino-8-oxodecanoyl) 
National Institutes of Health

Papers overview

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2017
2017
BACKGROUND Apicidin, as an inhibitor of histone deacetylase, showed a wide range of antiproliferative activity against various… 
2010
2010
It was recently reported that the reduced expression of hypoxia-inducible factor prolyl 4-hydroxylase PHD2 in human cancers… 
2009
2009
Histone deacetylase (HDAC) inhibitors are emerging as an exciting new class of potential anti-cancer agents for the treatment of… 
2008
2008
The cellular susceptibility of cancer cells to histone deacetylase (HDAC) inhibitors is increased by the etopic expression of… 
2007
2007
Some histone deacetylase inhibitors (HDACi) have recently been related to teratogenic effects in rodents. Skeletal defects have… 
2006
2006
Histone deacetylase (HDAC) inhibitors are promising anti-cancer drugs, but these exert differential responses depending on the… 
2005
2005
Apicidin, a fungal metabolite isolated from Fusarium pallidoroseum, is a cyclic tetrapeptide that exhibits potent anti-protozoal… 
2004
2004
Apicidin, a histone deacetylase inhibitor, is a novel cyclic tetrapeptide with potent antiproliferative activity against various… 
Highly Cited
2000
Highly Cited
2000
Apicidin's indole was efficiently converted into a series of N-substituted quinolone derivatives by indole N-alkylation followed…