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apicidin

Known as: cyclo(N-O-methyl-tryptophyl-isoleucyl-pipecolinyl-2-amino-8-oxodecanoyl) 
 
National Institutes of Health

Papers overview

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2011
2011
ABSTRACT Prion sorption to soil is thought to play an important role in the transmission of scrapie and chronic wasting disease… Expand
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Highly Cited
2008
Highly Cited
2008
AIMS Recent studies have demonstrated the importance of chromatin remodelling via histone acetylation/deacetylation for the… Expand
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Highly Cited
2008
Highly Cited
2008
The human HDAC (histone deacetylase) family, a well-validated anticancer target, plays a key role in the control of gene… Expand
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2008
2008
The histone deacetylase (HDAC) inhibitor, apicidin, has been shown to suppress the growth of human breast cancer cells. In this… Expand
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Highly Cited
2004
Highly Cited
2004
Apicidin has been identified as a histone deacetylase (HDAC) inhibitor. Since HDAC inhibitors are emerging as an exciting new… Expand
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Highly Cited
2003
Highly Cited
2003
Effects of the histone deacetylase (HDAC) inhibitor MS-275 have been examined in human leukemia and lymphoma cells (U937, HL-60… Expand
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Highly Cited
2003
Highly Cited
2003
Pharmacologic stimulation of fetal hemoglobin (HbF) expression may be a promising approach for the treatment of beta-thalassemia… Expand
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Highly Cited
2002
Highly Cited
2002
We previously reported that apicidin arrested human cancer cell growth through selective induction of p21WAF1/Cip1. In this study… Expand
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Highly Cited
2000
Highly Cited
2000
Apicidin [cyclo(N-O-methyl-L-tryptophanyl-L-isoleucinyl-D-pipecolinyl -L-2-amino-8-oxodecanoyl)] is a fungal metabolite shown to… Expand
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Highly Cited
1996
Highly Cited
1996
A novel fungal metabolite, apicidin [cyclo(N-O-methyl-L-tryptophanyl-L -isoleucinyl-D-pipecolinyl-L-2-amino-8-oxodecanoyl)], that… Expand
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