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apicidin

Known as: cyclo(N-O-methyl-tryptophyl-isoleucyl-pipecolinyl-2-amino-8-oxodecanoyl) 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2017
051019962017

Related topics

Related topics

3 relations

Broader (2)

Cyclic PeptidesHistone deacetylase inhibitor

Narrower (1)

apicidin C

Related mentions per year

Related mentions per year

1955-2018
1960198020002020
apicidin
Cyclic Peptides
Histone deacetylase inhibitor
apicidin C

Papers overview

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Highly Cited
2008
Highly Cited
2008
Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors.
The human HDAC (histone deacetylase) family, a well-validated anticancer target, plays a key role in the control of gene… (More)
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2008
2008
Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure.
AIMS Recent studies have demonstrated the importance of chromatin remodelling via histone acetylation/deacetylation for the… (More)
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2004
2004
Apicidin is a histone deacetylase inhibitor with anti-invasive and anti-angiogenic potentials.
Apicidin has been identified as a histone deacetylase (HDAC) inhibitor. Since HDAC inhibitors are emerging as an exciting new… (More)
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2003
2003
Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin.
Pharmacologic stimulation of fetal hemoglobin (HbF) expression may be a promising approach for the treatment of beta-thalassemia… (More)
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Highly Cited
2003
Highly Cited
2003
The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1…
Effects of the histone deacetylase (HDAC) inhibitor MS-275 have been examined in human leukemia and lymphoma cells (U937, HL-60… (More)
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Highly Cited
2002
Highly Cited
2002
Apicidin, a histone deacetylase inhibitor, induces apoptosis and Fas/Fas ligand expression in human acute promyelocytic leukemia cells.
We previously reported that apicidin arrested human cancer cell growth through selective induction of p21(WAF1/Cip1). In this… (More)
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2001
2001
Activation of p21(WAF1/Cip1) transcription through Sp1 sites by histone deacetylase inhibitor apicidin: involvement of protein kinase C.
We previously reported that apicidin, a novel histone deacetylase inhibitor, inhibited the proliferation of tumor cells via… (More)
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Highly Cited
2000
Highly Cited
2000
Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin.
Apicidin [cyclo(N-O-methyl-L-tryptophanyl-L-isoleucinyl-D-pipecolinyl -L-2-amino-8-oxodecanoyl)] is a fungal metabolite shown to… (More)
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1999
1999
A hemorrhagic factor (Apicidin) produced by toxic Fusarium isolates from soybean seeds.
Fifty-two isolates of Fusarium species were obtained from soybean seeds from various parts of Korea and identified as Fusarium… (More)
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Highly Cited
1996
Highly Cited
1996
Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase.
A novel fungal metabolite, apicidin [cyclo(N-O-methyl-L-tryptophanyl-L -isoleucinyl-D-pipecolinyl-L-2-amino-8-oxodecanoyl)], that… (More)
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