Semantic Scholar uses AI to extract papers important to this topic.
The human HDAC (histone deacetylase) family, a well-validated anticancer target, plays a key role in the control of gene… Expand AIMS
Recent studies have demonstrated the importance of chromatin remodelling via histone acetylation/deacetylation for the… Expand Apicidin has been identified as a histone deacetylase (HDAC) inhibitor. Since HDAC inhibitors are emerging as an exciting new… Expand Effects of the histone deacetylase (HDAC) inhibitor MS-275 have been examined in human leukemia and lymphoma cells (U937, HL-60… Expand Pharmacologic stimulation of fetal hemoglobin (HbF) expression may be a promising approach for the treatment of beta-thalassemia… Expand We previously reported that apicidin arrested human cancer cell growth through selective induction of p21WAF1/Cip1. In this study… Expand [structure: see text]. Isolation and structure elucidation of two novel cyclic tetrapeptides that show a variety of potent… Expand Apicidin [cyclo(N-O-methyl-L-tryptophanyl-L-isoleucinyl-D-pipecolinyl -L-2-amino-8-oxodecanoyl)] is a fungal metabolite shown to… Expand Cancer metastasis represents the most important cause of cancer death and agents that may inhibit tumor cell invasion have been… Expand A novel fungal metabolite, apicidin [cyclo(N-O-methyl-L-tryptophanyl-L -isoleucinyl-D-pipecolinyl-L-2-amino-8-oxodecanoyl)], that… Expand