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apicidin

Known as: cyclo(N-O-methyl-tryptophyl-isoleucyl-pipecolinyl-2-amino-8-oxodecanoyl) 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
The human HDAC (histone deacetylase) family, a well-validated anticancer target, plays a key role in the control of gene… Expand
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Highly Cited
2008
Highly Cited
2008
AIMS Recent studies have demonstrated the importance of chromatin remodelling via histone acetylation/deacetylation for the… Expand
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Highly Cited
2004
Highly Cited
2004
Apicidin has been identified as a histone deacetylase (HDAC) inhibitor. Since HDAC inhibitors are emerging as an exciting new… Expand
Highly Cited
2003
Highly Cited
2003
Effects of the histone deacetylase (HDAC) inhibitor MS-275 have been examined in human leukemia and lymphoma cells (U937, HL-60… Expand
Highly Cited
2003
Highly Cited
2003
Pharmacologic stimulation of fetal hemoglobin (HbF) expression may be a promising approach for the treatment of beta-thalassemia… Expand
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Highly Cited
2002
Highly Cited
2002
We previously reported that apicidin arrested human cancer cell growth through selective induction of p21WAF1/Cip1. In this study… Expand
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2001
2001
[structure: see text]. Isolation and structure elucidation of two novel cyclic tetrapeptides that show a variety of potent… Expand
Highly Cited
2000
Highly Cited
2000
Apicidin [cyclo(N-O-methyl-L-tryptophanyl-L-isoleucinyl-D-pipecolinyl -L-2-amino-8-oxodecanoyl)] is a fungal metabolite shown to… Expand
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Highly Cited
2000
Highly Cited
2000
Cancer metastasis represents the most important cause of cancer death and agents that may inhibit tumor cell invasion have been… Expand
Highly Cited
1996
Highly Cited
1996
A novel fungal metabolite, apicidin [cyclo(N-O-methyl-L-tryptophanyl-L -isoleucinyl-D-pipecolinyl-L-2-amino-8-oxodecanoyl)], that… Expand
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