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antibiotic APHE 1

Known as: 3-ethyl-1H-pyrazolo(2,3-b)isoquinolin-9-one, APHE-1 
National Institutes of Health

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2 relations

Broader (2)

IsoquinolinesPyrazoles

Papers overview

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2006
2006
TAXONOMY , FERMENTATION , ISOLATION AND BIOLOGICAL ACTIVITY
APHE-1and APHE-2exhibited in vitro antitumor activity against tumor cell lines of mice and human origin. Moreover, these… 
2000
2000
APHE-3, a spore-associated antibiotic of Streptomyces griseocarneus NCIMB 40447
Abstract Solid cultures of the producing strain grown on Bennett medium develop abundant mycelium and intense sporulation. Under… 
1999
1999
Nutritional requirements for the production of pyrazoloisoquinolinone antibiotics by Streptomyces griseocarneus NCIMB 40447
Abstract This paper describes the effect of different nutrients on the production of pyrazoloisoquinolinone antibiotics (APHE) by… 
1992
1992
APHE-1 and APHE-2, two new antimicrobial and cytotoxic antibiotics. II. Physico-chemical properties and structure elucidation.
Two new pyrazolo-isoquinolinone antibiotics, APHE-1 and APHE-2, have been isolated from the culture filtrate and mycelia of… 
1992
1992
APHE-1 and APHE-2, two new antimicrobial and cytotoxic antibiotics. I. Taxonomy, fermentation, isolation and biological activity.
APHE-1 and APHE-2 are two new antibiotics produced by Streptoverticillium griseocarneum NCIMB 40447. They exhibited a remarkable… 
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