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aminothiol

National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

AminesSulfhydryl Compounds
Cystamine

Narrower (1)

Cysteamine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Synthesis of the Alkaloid Natural Products (+)-Plicane and (-)-Obliquine, Using Polymer-Supported Reagents and Scavengers
Two new naturally occurring amaryllidaceae alkaloids have been synthesized, using a divergent approach facilitated by the use of… 
2003
2003
The Cytoprotective Aminothiol WR1065 Activates p53 through a Non-genotoxic Signaling Pathway Involving c-Jun N-terminal Kinase*
WR1065 is an aminothiol with selective cytoprotective effects in normal cells compared with cancer cells. In a previous study… 
Highly Cited
2002
Highly Cited
2002
Restoration of wild‐type conformation and activity of a temperature‐sensitive mutant of p53 (p53V272M) by the cytoprotective aminothiol WR1065 in the esophageal cancer cell line TE‐1
The aminothiol WR1065, the active metabolite of the cytoprotector amifostine, exerts its antimutagenic effects through free… 
2001
2001
Determination of biologically active low-molecular-mass thiols in human blood. III. Highly sensitive narrow-bore isocratic reversed-phase high-performance liquid chromatography with fluorescence…
2001
2001
Selective radioprotection of hepatocytes by systemic and portal vein infusions of amifostine in a rat liver tumor model.
Highly Cited
2000
Highly Cited
2000
Qualitative and quantitative determination of biologically active low-molecular-mass thiols in human blood by reversed-phase high-performance liquid chromatography with photometry and fluorescence…
2000
2000
Determination of biologically active low-molecular-mass thiols in human blood. II. High-performance capillary electrophoresis with photometric detection.
Highly Cited
1989
Highly Cited
1989
Clinical trials of WR-2721 and cis-platinum.
1989
1989
Conformational changes in chromatin structure induced by the radioprotective aminothiol, WR 1065.
WR 1065, 2-[(minopropyl) amino] ethanethiol is an effective scavenger of free radicals. When present during irradiation it… 
1983
1983
Modification of the radiation response of the mouse kidney by misonidazole and WR-2721.
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