Cystamine

Known as: Cystamine [Chemical/Ingredient], 2,2'-Dithiobis(ethylamine), Decarboxycystine 
A radiation-protective agent that interferes with sulfhydryl enzymes. It may also protect against carbon tetrachloride liver damage.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1951-2018
010203019512017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Accumulation of unwanted/misfolded proteins in aggregates has been observed in airways of patients with cystic fibrosis (CF), a… (More)
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2007
2007
BACKGROUND/AIMS We investigated whether the tissue transglutaminase inhibitor cystamine is able to inhibit remodelling of small… (More)
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Highly Cited
2006
Highly Cited
2006
There is no treatment for the neurodegenerative disorder Huntington disease (HD). Cystamine is a candidate drug; however, the… (More)
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2005
2005
Cystamine is neuroprotective in a number of models of neurodegeneration. The therapeutic benefit of cystamine has been attributed… (More)
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2005
2005
Huntington disease (HD) is an adult onset neurodegenerative disorder characterized by selective atrophy and cell loss within the… (More)
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Highly Cited
2004
Highly Cited
2004
Cystamine, a small disulfide-containing chemical, is neuroprotective in a transgenic mouse and a Drosophila model of Huntington's… (More)
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Highly Cited
2003
Highly Cited
2003
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by an abnormally expended polyglutamine… (More)
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Highly Cited
2002
Highly Cited
2002
The precise cause of neuronal death in Huntington's disease (HD) is unknown. Proteolytic products of the huntingtin protein can… (More)
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Highly Cited
2002
Highly Cited
2002
Since its introduction in 1959, Ellman's reagent (5,5'-dithio-bis(2-nitrobenzoic acid)) has been the favorite reagent for… (More)
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Highly Cited
1978
Highly Cited
1978
Cellulose acetate electrophoresis of mouse hemoglobins modified with the disulfide reagent cystamine permits rapid, unequivocal… (More)
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