aminochrome 1

Known as: 2,3-dihydro-6-hydroxy-5H-indol-5-one, aminochrome, dopaminochrome 
 
National Institutes of Health

Papers overview

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2015
2015
It was reported that aminochrome induces the formation of alpha synuclein (SNCA) oligomers during dopamine oxidation. We found… (More)
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2012
2012
Hallmarks of idiopathic and some forms of familial Parkinson’s disease are mitochondrial dysfunction, iron accumulation and… (More)
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2005
2005
We report a new and specific mechanism for iron-mediated neurotoxicity using RCHT cells, which were derived from rat hypothalamus… (More)
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Highly Cited
2001
Highly Cited
2001
The mechanism of copper (Cu) neurotoxicity was studied in the RCSN-3 neuronal dopaminergic cell line, derived from substantia… (More)
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2001
2001
We present for discussion a possible molecular mechanism explaining the formation of reactive oxygen species involved in the… (More)
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Highly Cited
1997
Highly Cited
1997
Tyrosinase (EC 1.14.18.1) exhibits unusual kinetic properties in the oxidation of monohydric phenol substrates consisting of a… (More)
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1997
1997
Human glutathione transferases (GSTs) were shown to catalyze the reductive glutathione conjugation of aminochrome (2, 3… (More)
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Highly Cited
1995
Highly Cited
1995
An enzyme responsible for the oxidation of dopamine and formation of neuromelanin in brain has not been identified. Prostaglandin… (More)
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1995
1995
The presence of 5-Hydroxydopamine (5-OHDA) and 6-Hydroxydopamine (6-OHDA) in the urine of parkinsonian patients on levodopa… (More)
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1981
1981
Autoxidation of dopamine as measured by its aminochrome formation at 480 nm was considerably potentiated by Mn++ in comparison to… (More)
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