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alniditan

Known as: N-(3,4-dihydro-2H-1-benzopyran-2-yl methyl)-N'-(1,4,5,6-tetrahydro-2-pyrimidinyl)-1,3-propanediamine dihydrochloride 
A benzopyran lacking the indole ring of the triptans with vasoconstrictor activity. Alnitidan selectively binds to and activates serotonin 5-HT 1B… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

BenzopyransPropylaminesPyrimidines

Narrower (1)

R 091274

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Correction to: Therapeutic novelties in migraine: new drugs, new hope?
After publication of the original article 1, the authors have notified us that the row corresponding to the “Alniditan” drug… 
2002
2002
Molecular cloning and expression of the porcine trigeminal ganglion cDNA encoding a 5-ht(1F) receptor.
Using a combination of reverse transcription polymerase chain reaction (RT-PCR) and inverse-PCR techniques, we amplified, cloned… 
2001
2001
Treatment of Migraine Attacks with Intranasal Alniditan: An Open Study
In this open phase-II clinical tolerability trial 17 neurologists enrolled a total of 112 patients and instructed them to… 
2000
2000
5-HT1A and 5-HT1B/1D receptors are involved in the modulation of the trigeminovascular system of the cat: a microiontophoretic study
1998
1998
Transdermal alniditan delivery by skin electroporation.
Review
1997
Review
1997
Acute migraine therapy: the newer drugs
In 1996, our knowledge of acute antimigraine therapy expanded in three major areas. First, large surveys have confirmed the… 
1996
1996
Alniditan in the Acute Treatment of Migraine Attacks
Alniditan is a new 5HT1D receptor agonist, belonging to a different chemical class from sumatriptan and other indole derivatives… 
1996
1996
Transdermal Permeation of Alniditan by Iontophoresis: In Vitro Optimization and Human Pharmacokinetic Data
AbstractPurpose. The aim of this paper was to assess the feasibility of electrically enhanced transdermal delivery of alniditan… 
1996
1996
Monthly Update: Central & Peripheral Nervous Systems: Pharmacology of antimigraine 5-HT1D receptor agonists
The 5-HT 1D receptor agonist sumatriptan is undoubtedly a significant advance in the management of migraine and cluster attacks… 
1996
1996
Selective vasoconstriction by alniditan in the carotid vascular bed of anaesthetized dogs.
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