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Typing of Methicillin resistant Staphylococcus aureus: a technical review.
TLDR
There is no consensus regarding the single best method for typing of MRSA strains and a need for harmonisation of typing techniques by following standard protocols is emphasised to establish surveillance networks and facilitate global MRSA control.
Molecular typing of methicillin-resistant Staphylococcus aureus strains by PCR-RFLP of SPA gene: a reference laboratory perspective.
TLDR
The study demonstrates the importance of spa genotyping in the discrimination of MRSA strains, which were otherwise indistinguishable by bacteriophage typing.
Epidemilogical analysis of Neisseria gonorrhoeae isolates by antimicrobial susceptibility testing, auxotyping and serotyping.
TLDR
Although A/S typing had the highest discriminatory index, isolates recovered from index case and their sexual contacts were found to be identical by all typing methods.
Characterization of Sumatriptan-Induced Contractions in Human Isolated Blood Vessels Using Selective 5-HT1B and 5-HT1D Receptor Antagonists and In Situ Hybridization
TLDR
Results show that the 5-HT1B receptor is primarily involved in sumatriptan-induced contractions of human cranial as well as peripheral blood vessels.
Yeast identification in routine clinical microbiology laboratory and its clinical relevance.
TLDR
The algorithm followed was helpful in timely presumptive identification and final diagnosis of yeast infections, including multi-species yeast infections.
Development of TaqMan real-time polymerase chain reaction for the detection of the newly emerging form of carbapenem resistance gene in clinical isolates of Escherichia coli, Klebsiella pneumoniae,
TLDR
The study demonstrates that real-time PCR assay based on TaqMan chemistry is a useful technique for the detection of bla NDM-1 harbouring clinical isolates of E. coli, K. pneumoniae and A. baumannii.
REDD1 functions at the crossroads between the therapeutic and adverse effects of topical glucocorticoids
TLDR
This work identifies stress‐inducible mTOR inhibitor REDD1 (regulated in development and DNA damage response 1) as a major molecular target of glucocorticoids, which mediates cutaneous atrophy, and suggests that combining steroids withREDD1 inhibitors may yield a novel, safer glucOCorticoid‐based therapies.
Differential targeting of androgen and glucocorticoid receptors induces ER stress and apoptosis in prostate cancer cells
TLDR
The data validate the concept of dual AR/GR targeting in prostate cancer (PC) and suggest that BZ combination with dual-target steroid receptor modulator CpdA has high potential for PC therapy.
Correlation between In vitro susceptibility and treatment outcome with azithromycin in gonorrhoea: a prospective study.
TLDR
Results of the study indicate that 2 g single oral dose azithromycin is safe and effective in the treatment of uncomplicated gonorrhoea.
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