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acrivastine

Known as: acrivastine [Chemical/Ingredient], 2-Propenoic acid, 3-(6-(1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)-2-pyridinyl)-, (E,E)-, (E)-6-((E)-3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)-2-pyridineacrylic Acid 
A synthetic alkylamine with non-sedative antihistaminergic activity. Acrivastine competitively blocks the histamine H1 receptor and limits the… 
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (1)

BW 825C
Coronary heart diseaseDrug AllergyHistamine H1 Receptor Antagonists [MoA]Hypertensive disease

Broader (2)

Histamine H1 Antagonists, Non-SedatingTriprolidine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Small molecule analysis using laser desorption/ionization mass spectrometry on nano-coated silicon with self-assembled monolayers.
Highly Cited
2007
Highly Cited
2007
Acrivastine, terfenadine and diphenhydramine effects on driving performance as a function of dose and time after dosing
The study was conducted according to a nineway, observer- and subject-blind, cross-over design. Its purpose was to compare the… 
2004
2004
Evaluation and Comparison of Five Matrix Excipients for the Controlled Release of Acrivastine and Pseudoephedrine
For treatment of allergic rhinitis, acrivastine with pseudoephedrine in Semprex®‐D conventional capsules requires dosing every 6… 
2004
2004
The effects of acrivastine (BW825C), diphenhydramine and terfenadine in combination with alcohol on human CNS performance
SummaryTwo studies were performed to measure the effects of acrivastine (BW825C), an antihistamine, in combination with alcohol… 
2000
2000
Onset-of-action for antihistamine and decongestant combinations during an outdoor challenge.
Review
1999
Review
1999
Cardiac ion channels and antihistamines: possible mechanisms of cardiotoxicity
Despite the enormous success of second generation antihistamines, in the mid‐1980s, about 10 years after their introduction in… 
1994
1994
Time of onset of action of acrivastine in the skin of pollen‐allergic subjects
The purpose of this study was to assess the time of onset of action of acrivastine in suppressing the wheal response to histamine… 
1990
1990
A cross-over comparison of acrivastine, pseudoephedrine and their combination in seasonal allergic rhinitis.
In a four period, double-blind cross-over study, forty patients with moderate to severe symptoms of seasonal allergic rhinitis… 
Review
1989
Review
1989
Acrivastine in allergic rhinitis: a review of clinical experience.
Acrivastine is an antihistamine with reduced sedating potential. This comprehensive review of clinical experience with… 
1988
1988
Acrivastine in Seasonal Allergic Rhinitis: Two Randomized Crossover Studies to Evaluate Efficacy and Safety
In two randomized crossover studies, the antihistamine, acrivastine, was evaluated for the treatment of seasonal allergic… 
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