acodazole

Known as: 1H-imidazo[4,5-f]quinoline, acetamide deriv, acetamide, N-methyl-N-[4-[(7-methyl-1H-imidazo[4, 5-f]quinolin-9-yl)amino]phenyl]- 
A synthetic imidazoquinoline with antineoplastic activity. Acodazole intercalates into DNA, resulting in disruption of DNA replication. Use of this… (More)
National Institutes of Health

Papers overview

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2008
2008
Chronic microglial activation is an important component of many neurological disorders, and imaging activated microglia in vivo… (More)
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Review
2006
Review
2006
There is a remarkable array of new chemical entities in the current antiepileptic drug (AED) development pipeline. In some cases… (More)
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Highly Cited
2006
Highly Cited
2006
Increased Rho kinase (ROCK) activity contributes to smooth muscle contraction and regulates blood pressure homeostasis. We… (More)
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Highly Cited
2004
Highly Cited
2004
An orthotopic mouse model of cervical carcinoma has been used to investigate the relationship between acute (cyclic) hypoxia and… (More)
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Highly Cited
2003
Highly Cited
2003
Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C… (More)
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2003
2003
The aim of the present study was to investigate the impact of four different lactobacillus (LB) strains, namely Lactobacillus… (More)
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Highly Cited
2001
Highly Cited
2001
The vascular endothelial cell is believed to be a major target cell of radiation-induced injury to the central nervous system… (More)
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1997
1997
A C6 glioma cell line stably transfected with the rat delta opioid receptor (C6delta) was used to characterize receptor binding… (More)
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Highly Cited
1991
Highly Cited
1991
1. Conventional intracellular and extracellular recording techniques were used to investigate the physiology and pharmacology of… (More)
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Highly Cited
1971
Highly Cited
1971
A dietary regimen containing the carcinogen N-2@fluorenyl acetamide for the induction of hyperplastic hepatic nodules and… (More)
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