acetylenic carbamate

Known as: 1,1-Diphenyl-2-propynyl-N-cyclohexylcarbamate, 1,1-diphenyl-2-propynyl cyclohexylcarbamate, ENPROMATE 
A synthetic acetylenic carbamate, an alkylating agent, with antineoplastic activity.
National Institutes of Health

Papers overview

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2010
2010
BACKGROUND AND PURPOSE Cannabinoid receptor agonists reduce intestinal propulsion in rodents through the CB(1) receptor. In… (More)
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Highly Cited
2009
Highly Cited
2009
The present study investigated whether inhibition of fatty acid amide hydrolase (FAAH), the enzyme responsible for anandamide… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND AND PURPOSE The endocannabinoid N-arachidonoylethanolamide (anandamide) is co-synthesized with other N… (More)
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2008
2008
Analysis of the x-ray crystal structure of mono-substituted acetylenic thienopyrimidine 6 complexed with the ErbB family enzyme… (More)
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2008
2008
BACKGROUND AND PURPOSE We have previously demonstrated antinociceptive effects of fatty acid amide hydrolase (FAAH) inhibition… (More)
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Highly Cited
2007
Highly Cited
2007
The endocannabinoids (eCBs) anandamide and 2-arachidonoyl glycerol (2-AG) are inactivated by a two-step mechanism. First, they… (More)
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2006
2006
Inhibitors of the enzyme fatty acid amide hydrolase (FAAH), the principal enzyme involved in the metabolism of the endogenous… (More)
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2000
2000
This study demonstrated that plant extracts containing acetylenic isobutylamides and polyacetylenes, previously reported as… (More)
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1996
1996
Inverse agonists are ligands that are capable of repressing basal receptor activity in the absence of an agonist. We have… (More)
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