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acetylenic carbamate

Known as: 1,1-Diphenyl-2-propynyl-N-cyclohexylcarbamate, 1,1-diphenyl-2-propynyl cyclohexylcarbamate, ENPROMATE 
A synthetic acetylenic carbamate, an alkylating agent, with antineoplastic activity.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
3.1.2. From Vinylic Grignard Reagents 1437 3.1.3. From Aryl Halides and Alkenyl Acetates 1438 3.2. Aryl-Aryl Cross-coupling 1438… Expand
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Highly Cited
2010
Highly Cited
2010
A series of acetylenic chalcones were evaluated for antimalarial and antitubercular activity. The antimalarial data for this… Expand
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Highly Cited
2009
Highly Cited
2009
The present study investigated whether inhibition of fatty acid amide hydrolase (FAAH), the enzyme responsible for anandamide… Expand
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Highly Cited
2008
Highly Cited
2008
The endocannabinoid N‐arachidonoylethanolamide (anandamide) is co‐synthesized with other N‐acylethanolamides, namely N… Expand
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Highly Cited
2008
Highly Cited
2008
We have previously demonstrated antinociceptive effects of fatty acid amide hydrolase (FAAH) inhibition that were accompanied by… Expand
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Highly Cited
2007
Highly Cited
2007
The endocannabinoids (eCBs) anandamide and 2-arachidonoyl glycerol (2-AG) are inactivated by a two-step mechanism. First, they… Expand
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Highly Cited
2006
Highly Cited
2006
Highly substituted 1H-isochromenes, isobenzofurans, and pyranopyridines can be prepared by allowing o-(1-alkynyl… Expand
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Highly Cited
2003
Highly Cited
2003
The reactivity of a variety of quinuclidine-based catalysts in the Baylis-Hillman reaction has been examined, and a… Expand
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Highly Cited
2000
Highly Cited
2000
This study demonstrated that plant extracts containing acetylenic isobutylamides and polyacetylenes, previously reported as… Expand
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Highly Cited
1996
Highly Cited
1996
Inverse agonists are ligands that are capable of repressing basal receptor activity in the absence of an agonist. We have… Expand
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