acetyl-CoA C-acyltransferase activity

Known as: 2-keto-acyl thiolase activity, beta-ketoadipyl-CoA thiolase activity, 3-ketoacyl CoA thiolase activity 
Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA. [EC:2.3.1.16]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1966-2018
010203019662018

Papers overview

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2009
2009
Little is known about what enzyme complexes or mechanisms control global lysine acetylation in the amino-terminal tails of the… (More)
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2008
2008
Inflammation-mediated dysregulation of the kynurenine pathway has been implicated as a contributor to a number of major brain… (More)
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2007
2007
The tryptophan metabolite kynurenic acid (KYNA), which is produced enzymatically by the irreversible transamination of l… (More)
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Highly Cited
2007
Highly Cited
2007
Kynurenic acid (KYNA), a metabolite of the kynurenine pathway of tryptophan degradation, is a neuroinhibitory agent present in… (More)
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2006
2006
Kynurenine aminotransferase (KAT) is an enzyme responsible for synthesis of kynurenic acid (KYNA), a well established… (More)
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Highly Cited
2001
Highly Cited
2001
3-ketoacyl-CoA thiolase (KAT) (EC: 2.3.1.16) catalyses a key step in fatty acid beta-oxidation. Expression of the Arabidopsis… (More)
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Highly Cited
2000
Highly Cited
2000
Trimetazidine is a clinically effective antianginal agent that has no negative inotropic or vasodilator properties. Although it… (More)
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Highly Cited
1999
Highly Cited
1999
L-kynurenine (L-KYN) serves as a substrate for the synthesis of neurotoxic 3-OH-kynurenine (3-OH-KYN) and neuroprotective… (More)
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Highly Cited
1997
Highly Cited
1997
The endogenous neuroprotectant kynurenic acid (KYNA) is produced by irreversible transamination of L-kynurenine (KYN). In the… (More)
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Highly Cited
1991
Highly Cited
1991
Using Tris-acetate buffer rather than conventional phosphate buffer, it was possible to detect two distinct proteins capable of… (More)
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