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acetyl-CoA C-acyltransferase activity

Known as: 2-keto-acyl thiolase activity, beta-ketoadipyl-CoA thiolase activity, 3-ketoacyl CoA thiolase activity 
Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA. [EC:2.3.1.16]
National Institutes of Health

Papers overview

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2019
2019
Discordant Effects of Putative Lysine Acetyltransferase Inhibitors in Biochemical and Living Systems
Lysine acetyltransferases (KATs) are exquisitely fine-tuned to target specific lysine residues on many proteins, including… 
2003
2003
Identification and Characterization of KAT, a Novel Gene Preferentially Expressed in Several Human Cancer Cell Lines
Abstract We describe the molecular characterization of a novel human gene on chromosome 1q23.3, termed KAT, which is highly… 
2000
2000
Beta-ketothiolase genes in Azotobacter vinelandii.
Azotobacter vinelandii is proposed to contain a single beta-ketothiolase activity participating in the formation of acetoacetyl… 
1998
1998
Molecular Cloning of Sucrase-Isomaltase cDNA in the House Musk Shrew Suncus murinus and Identification of a Mutation Responsible for Isolated Sucrase Deficiency*
Isolated sucrase deficiency has been demonstrated in a line of house musk shrew, Suncus murinus (laboratory name: suncus). This… 
1996
1996
Immunoelectron microscopic observation of the behaviors of peroxisomal enzymes inducibly synthesized in an n-alkane-utilizable yeast cell, Candida tropicalis.
We reported that immunoelectron microscopy was an excellent tool for determining the subcellular localization of thiolase… 
1996
1996
Long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency: A new method to identify the G1528C mutation in genomic DNA showing its high frequency (≈90%) and identification of a new mutation (T2198C)
Long-chain 3-hydroxyacyl-CoA dehydrogenase (LC3HAD) is not a monofunctional enzyme like all the other enzymes involved in… 
1995
1995
Cloning and characterization of a soluble kynurenine aminotransferase from rat brain: identity with kidney cysteine conjugate beta-lyase.
In this study, we describe the cloning and characterization of a soluble form of kynurenine aminotransferase (KAT, EC 2.6.1.7… 
Highly Cited
1988
Highly Cited
1988
Transient kinetics of heparin-catalyzed protease inactivation by antithrombin III. Linkage of protease-inhibitor-heparin interactions in the reaction with thrombin.
Heparin (H) was previously shown to accelerate the inactivation of alpha-thrombin (T) by antithrombin III (AT) primarily by… 
1986
1986
Deficient beta-ketothiolase activity in leukocytes from a patient with 2-methylacetoacetic aciduria.
1975
1975
Kinetics and properties of beta-ketothiolase from Clostridium pasteurianum.
1. Beta-Ketothiolase of Clostridium pasteurianum was purified 130-fold by ammonium sulphate fractionation and by column… 
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