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acetaminophen overdose

Known as: overdose acetaminophen, acetaminophen overdoses, paracetamol overdose 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Acetaminophen induced renal injury via oxidative stress and TNF-alpha production: therapeutic potential of arjunolic acid.
Review
2009
Review
2009
Hepatotoxicity despite early administration of intravenous N-acetylcysteine for acute acetaminophen overdose.
OBJECTIVES The objective was to evaluate the effectiveness of intravenous N-acetylcysteine (IV NAC; 300 mg/kg over 21 hours) in… 
Highly Cited
2008
Highly Cited
2008
Lower incidence of anaphylactoid reactions to N-acetylcysteine in patients with high acetaminophen concentrations after overdose
Background. Mechanisms responsible for anaphylactoid reactions to N-acetylcysteine (NAC) are poorly understood, and acetaminophen… 
Highly Cited
2005
Highly Cited
2005
Blood lactate but not serum phosphate levels can predict patient outcome in fulminant hepatic failure
Early identification of those patients with fulminant hepatic liver failure (FHF) who need a transplant greatly helps in their… 
Review
2005
Review
2005
The Therapeutic Use of Acetaminophen in Patients with Liver Disease
Acetaminophen has been used safely and effectively for many years to manage pain and/or fever in patients of all ages. It is… 
Highly Cited
2002
Highly Cited
2002
Reduction of toxic metabolite formation of acetaminophen.
Acetaminophen is a widely used over-the-counter drug that causes severe hepatic damage upon overdose. Cytochrome P450-dependent… 
Review
1999
Review
1999
Treatment of acetaminophen overdose.
The therapeutic management of patients with acetaminophen overdose is reviewed. Acetaminophen overdose results in more calls to… 
Highly Cited
1999
Highly Cited
1999
Etiology and outcome for 295 patients with acute liver failure in the United States.
Little information is available on acute liver failure (ALF) in the United States. We gathered demographic data retrospectively… 
Highly Cited
1989
Highly Cited
1989
Acute Acetaminophen Overdose During Pregnancy
During a nationwide acetaminophen overdose study conducted at the Rocky Mountain Poison and Drug Center from 1976-1985, 113… 
Highly Cited
1981
Highly Cited
1981
Age as a variable in acetaminophen overdose.
More than 300 accidental ingestions of acetaminophen products in children 6 years of age and younger have been reported to the… 
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