Body packing--the internal concealment of illicit drugs.
The transportation of illicit drugs by concealment within the body is now a common practice, and it has implications for clinical care. Body packers may ingest dozens of packets containing…
Nerve Agents: A Comprehensive Review
Nerve agents are perhaps the most feared of potential agents of chemical attack and the history, physical characteristics, pharmacology, clinical effects, and treatment are reviewed.
Goldfrank's Manual of Toxicologic Emergencies
General Approach to Medical Toxicology: Tools of the Trade The Biochemical, Molecular, and Pathophysiologic Basis of Medical Toxicology The Clinical Basis of Medical Toxicology Pharmaceuticals…
Extracorporeal Treatment for Lithium Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup.
- B. Decker, D. Goldfarb, M. Ghannoum
- MedicineAmerican Society of Nephrology. Clinical Journal
- 7 May 2015
The workgroup concluded that lithium is dialyzable (Level of evidence=A) and made the following recommendations: Hemodialysis is the preferred extracorporeal treatment, but continuous RRT is an acceptable alternative (1D).
Levamisole in cocaine: Unexpected news from an old acquaintance
The importance of accurately identifying levamisole-induced complications is therefore critical for symptomatic patients as discontinuation of exposure is fundamental and as a correct diagnosis prevents unnecessary and potentially dangerous use of other treatment modalities like powerful immunosuppressive therapy.
National academy of clinical biochemistry laboratory medicine practice guidelines: recommendations for the use of laboratory tests to support poisoned patients who present to the emergency department.
Recommendations for the use of clinical laboratory tests were prepared by an expert panel of analytical toxicologists and ED physicians specializing in clinical toxicology, and improvements are needed for immunoassays, particularly for amphetamines, benzodiazepines, opioids, and tricyclic antidepressants.
Severe Toxicity Following Synthetic Cannabinoid Ingestion
- J. Lapoint, L. James, C. Moran, L. Nelson, R. Hoffman, J. Moran
- MedicineClinical toxicology
- 1 October 2011
Ingestion of JWH-018 can produce seizures and tachyarrhythmias, and Clinicians, lawmakers, and the general public need to be aware of the potential for toxicity associated with synthetic cannabinoid use.
Extracorporeal Treatment for Metformin Poisoning: Systematic Review and Recommendations From the Extracorporeal Treatments in Poisoning Workgroup
Despite clinical evidence comprised mostly of case reports and suboptimal toxicokinetic data, the workgroup recommended extracorporeal removal in the case of severe metformin poisoning.
Resistant alcohol withdrawal: Does an unexpectedly large sedative requirement identify these patients early?
RAW patients require large doses of benzodiazepine administration, additional sedatives, and undergo complicated hospitalizations, according to physicians’ choices of therapy.
Clinical Effects of Synthetic Cannabinoid Receptor Agonists Compared with Marijuana in Emergency Department Patients with Acute Drug Overdose
- Milana Zaurova, R. Hoffman, D. Vlahov, A. Manini
- Medicine, PsychologyJournal of Medical Toxicology
- 2 June 2016
In the first clinical study comparing the adverse effects of SCRA overdose vs. marijuana controls in an ED population, it is found that SCRA overdoses had significantly pronounced neurotoxicity and cardiotoxicity compared with marijuana.