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abiraterone acetate

Known as: Abiraterone Acetate [Chemical/Ingredient] 
An orally active acetate salt of the steroidal compound abiraterone with antiandrogen activity. Abiraterone inhibits the enzymatic activity of… 
National Institutes of Health

Related topics

Related topics

16 relations

Broader (2)

Antineoplastic AgentsCytochrome P-450 Enzyme Inhibitors

Narrower (2)

CB 7630Zytiga
Cytochrome P450 17A1 Inhibitors [MoA]In BloodNCIt Antineoplastic Agent TerminologySteroid 17-alpha-Hydroxylase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Abiraterone-Associated Fulminant Liver Failure.
To the Editor: Prabhsimranjot Singh MBBS; Ankur Sinha MBBS; Tsering Gyalpo Lama Tamang MBBS; Abhinav B Chandra MD FACP; Yiwu Jim… 
2016
2016
Impact of Prior
  • 2016
  • Corpus ID: 8679699
The objective of this study was to investigate whether the prior use of a novel androgen receptor-axis-targeted (ARAT) agent with… 
2016
2016
Open-label phase II study evaluating the efficacy of concurrent administration of radium Ra 223 dichloride (Ra-223) and abiraterone acetate (AA) in men with castration-resistant prostate cancer (CRPC…
177 Background: Abiraterone Acetate (AA), a CYP17 inhibitor, further decreases serum testosterone for castrate resistant prostate… 
2016
2016
Novel RP-HPLC method for the quantification of abiraterone acetate
Simple, rapid, accurate and specific RP-HPLC method has been developed for quantitative estimation of Abiraterone acetate in bulk… 
2013
2013
Pharmaceutical compositions comprising abiraterone acetate
Exhibits reduced food effect and improved bioavailability, discloses a pharmaceutical composition comprising abiraterone acetate. 
2013
2013
Prostate cancer: Abiraterone benefit extends to bone-related symptoms
Abiraterone acetate not only improves survival, but also provides pain relief and delays the occurrence of skeletal-related… 
2012
2012
Erratum to: Abiraterone acetate: a guide to its use in metastatic castration-resistant prostate cancer
BACKGROUND While frameworks exist to assist clinicians in prescribing appropriately in older patients at risk of adverse drug… 
Review
2012
Review
2012
Abiraterone acetate in the treatment of metastatic castration-resistant prostate cancer: review of clinical data
Abiraterone acetate (AA), after metabolization to abiraterone, is an oral inhibitor of the cytochrome P450C17 (CYP17) complex. It… 
2010
2010
Molecular profiling of circulating tumor cells (CTC) in patients with castrate metastatic prostate cancer (CMPC) receiving abiraterone acetate (AA) after failure of docetaxel-based chemotherapy.
4635 Background: Molecular profiles show consistent reactivation of androgen receptor (AR) in CMPC in part through overexpression… 
2008
2008
Crossover pharmacokinetics (PK) study to assess oral administration of abiraterone acetate capsule and tablet formulations in fasted and fed states in patients with prostate cancer
5168 Background: Abiraterone acetate (A) is an oral compound with metabolites that selectively inhibit CYP 17(17OH/ 17,20 lyase…