abiraterone acetate

Known as: Abiraterone Acetate [Chemical/Ingredient] 
An orally active acetate salt of the steroidal compound abiraterone with antiandrogen activity. Abiraterone inhibits the enzymatic activity of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2018
05010019942018

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Abiraterone acetate, an androgen biosynthesis inhibitor, improves overall survival in patients with metastatic… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Androgen receptor (AR) signalling remains critically important in metastatic castration-resistant prostate cancer… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Abiraterone acetate improved overall survival in metastatic castration-resistant prostate cancer at a preplanned… (More)
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Highly Cited
2012
Highly Cited
2012
PURPOSE Persistent androgen signaling is implicated in castrate-resistant prostate cancer (CRPC) progression. This study aimed to… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Biosynthesis of extragonadal androgen may contribute to the progression of castration-resistant prostate cancer. We… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE The principal objective of this trial was to evaluate the antitumor activity of abiraterone acetate, an oral, specific… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE Persistence of ligand-mediated androgen receptor signaling has been documented in castration-resistant prostate cancers… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE It has been postulated that castration-resistant prostate cancer (CRPC) commonly remains hormone dependent. Abiraterone… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Studies indicate that castration-resistant prostate cancer (CRPC) remains driven by ligand-dependent androgen receptor… (More)
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Highly Cited
2004
Highly Cited
2004
A series of three dose escalating studies were conducted to investigate the ability of the 17α-hydroxylase/C17,20-lyase inhibitor… (More)
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