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abecarnil

Known as: isopropyl 6-benzyloxy-4-methoxymethyl-beta-carboline-3-carboxylate 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Anti-Anxiety AgentsAnticonvulsantsCarbolines

Papers overview

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Highly Cited
2000
Highly Cited
2000
A double-blind, placebo-controlled trial of abecarnil and diazepam in the treatment of patients with generalized anxiety disorder.
In a multicenter, double-blind trial, 310 patients who had received a diagnosis of generalized anxiety disorder were treated for… 
1997
1997
A double-blind evaluation of the safety and efficacy of abecarnil, alprazolam, and placebo in outpatients with generalized anxiety disorder. Abecarnil Work Group.
In a placebo-controlled, multicenter study, 180 male and female outpatients, ages 18-65, with DSM-III-R generalized anxiety… 
1997
1997
Discriminative Stimulus Properties of Ethanol in the Rat: Differential Effects of Selective and Nonselective Benzodiazepine Receptor Agonists
1996
1996
Isoniazid-induced Inhibition of GABAergic Transmission Enhances Neurosteroid Content in the Rat Brain
1996
1996
Further evidence for differences between non-selective and BZ-1 (ω1) Selective, benzodiazepine receptor ligands in murine models of “state” and “trait” Anxiety
1996
1996
Putative benzodiazepine partial agonists demonstrate receptor heterogeneity
1996
1996
Anticonvulsant profile of the imidazoquinazolines NNC 14-0185 and NNC 14-0189 in rats and mice.
1993
1993
Carbon dioxide inhalation, stress and anxiogenic drugs reduce the function of GABAA receptor complex in the rat brain
Review
1993
Review
1993
Abecarnil: a novel anxiolytic with mixed full agonist/partial agonist properties in animal models of anxiety and sedation.
Although the benzodiazepines are without doubt the most effective agents currently available for the treatment of anxiety… 
1993
1993
Human studies on abecarnil a new beta-carboline anxiolytic: safety, tolerability and preliminary pharmacological profile.
1. Abecarnil (isopropyl-6-benzyloxy-4-methoxymethyl-beta-carboline-3-carboxylate), a beta-carboline with high affinity for… 
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