Skip to search formSkip to main contentSkip to account menu

abecarnil

Known as: isopropyl 6-benzyloxy-4-methoxymethyl-beta-carboline-3-carboxylate 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Anti-Anxiety AgentsAnticonvulsantsCarbolines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
A double-blind, placebo-controlled trial of abecarnil and diazepam in the treatment of patients with generalized anxiety disorder.
In a multicenter, double-blind trial, 310 patients who had received a diagnosis of generalized anxiety disorder were treated for… 
1999
1999
Changes in the gene expression of GABAA receptor subunit mRNAs in the septum of rats subjected to pentylenetetrazol-induced kindling.
Highly Cited
1998
Highly Cited
1998
Modulation of γ-aminobutyric acid (GABA) receptors and the feeding response by neurosteroids in Hydra vulgaris
1996
1996
Isoniazid-induced Inhibition of GABAergic Transmission Enhances Neurosteroid Content in the Rat Brain
Highly Cited
1995
Highly Cited
1995
Modulation of basal and stress-induced release of acetylcholine and dopamine in rat brain by abecarnil and imidazenil, two anxioselective gamma-aminobutyric acidA receptor modulators.
The effects of imidazenil (6-(2-bromophenyl)-8-fluoro-4-H-imidazo[1-5-a][1-4]benzodiazepine-3- carboxamide) and abecarnil… 
Review
1995
Review
1995
Future directions in anxiolytic pharmacotherapy.
Highly Cited
1992
Highly Cited
1992
The first double-blind, placebo-controlled trial of a partial benzodiazepine agonist, abecarnil (ZK 112-119), in generalized anxiety disorder.
This is the first reported controlled trial of a partial benzodiazepine agonist, abecarnil, utilized in the treatment of… 
Highly Cited
1990
Highly Cited
1990
Abecarnil, a metabolically stable, anxioselective beta-carboline acting at benzodiazepine receptors.
Abecarnil (isopropyl 6-benzyloxy-4-methoxymethyl-beta-carboline-3-carboxylate) is a novel ligand for central benzodiazepine (BZ… 
Highly Cited
1990
Highly Cited
1990
Anticonvulsant action of the beta-carboline abecarnil: studies in rodents and baboon, Papio papio.
Abecarnil (ZK 112119; isopropyl-6-benzyloxy-4-methoxymethyl-beta-carboxylate) is a metabolically stable beta-carboline derivative… 
1990
1990
Pharmacokinetics, anticonvulsant efficacy and adverse effects of the beta-carboline abecarnil, a novel ligand for benzodiazepine receptors, after acute and chronic administration in dogs.
Abecarnil (ZK 112119; isopropyl-6-benzyloxy-4-methoxymethyl-beta-carboline-3-carboxylate), a novel beta-carboline with high… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)